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TranscriptomicsEffects of IGF 1 on primary breast fibroblasts (normal and carcinoma associated)
To characterize the effects of IGF 1 on primary breast fibroblasts, we cultured pre-starved primary breast fibroblasts (normal and carcinoma associated) from three patients with or without 50ng/ml IGF 1 for 24 h. We then profiled gene expression changes using Human Exonic Evidence Based Oligonucleot...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-18952 | biostudies-arrayexpress
TranscriptomicsEffects of IGF 1 on MCF-7 breast cancer cells
To characterize the effects of IGF 1 on MCF 7 breast cancer cells, we cultured pre-starved MCF 7 cells with or without 50ng/ml IGF 1 for 24 h. We then profiled gene expression changes using Human Exonic Evidence Based Oligonucleotide (HEEBO) microarrays. After stimulation, total RNA was extracted an...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-18953 | biostudies-arrayexpress
TranscriptomicsEffects of IGF 1 on primary breast fibroblasts, MCF-7 breast cancer cells and CCL-171 fibroblasts
This SuperSeries is composed of the following subset Series: GSE18952: Effects of IGF 1 on primary breast fibroblasts (normal and carcinoma associated) GSE18953: Effects of IGF 1 on MCF-7 breast cancer cells GSE18954: Effects of IGF 1 on CCL-171 fibroblasts Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-18955 | biostudies-arrayexpress
TranscriptomicsEffects of IGF 1 on CCL-171 fibroblasts
To characterize the effects of IGF 1 on CCL171 cells, we cultured pre-starved CCL 171 fibroblasts with or without 50ng/ml IGF 1 for 24 h. We then profiled gene expression changes using Human Exonic Evidence Based Oligonucleotide (HEEBO) microarrays. After stimulation, total RNA was extracted and amp...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-18954 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of heterotypic interactions between cancer cells and osteoblasts in vitro
Bone is the most common site of breast cancer metastasis, and this type of metastasis is a main cause of morbidity. Because breast cancer is a heterogeneous disease, the interactions between the cancer cells and the skeletal host cells, such as osteoblasts, might be diverse. Thus far, these tumor-os...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29036 | biostudies-arrayexpress
TranscriptomicsNormal human osteoblasts and MCF7 mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented malignant epithelial cell compartments (MCF7) and cells that represented skeletal compartments (Normal Human (NH) Osteoblasts) wer...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29032 | biostudies-arrayexpress
TranscriptomicsNormal human osteoblasts and MDA-MB-231 mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented malignant epithelial cell compartments (MDA-MB-231) and cells that represented skeletal compartments (Normal Human (NH) Osteoblast...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29033 | biostudies-arrayexpress
TranscriptomicsNormal human osteoblasts and SKBR3 mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented malignant epithelial cell compartments (SKBR3) and cells that represented skeletal compartments (Normal Human (NH) Osteoblasts) we...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29034 | biostudies-arrayexpress
TranscriptomicsNormal human osteoblasts and T47D mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented malignant epithelial cell compartments (T47D) and cells that represented skeletal compartments (Normal Human (NH) Osteoblasts) wer...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29035 | biostudies-arrayexpress
TranscriptomicsNormal human osteoblasts and HMEC mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented healthy epithelial cell compartments (HMEC - human mammary epithelial cell) and cells that represented skeletal compartments (Norm...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29030 | biostudies-arrayexpress
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