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Unknown14. Effects of an Opt-Out Protocol for Antibiotic De-escalation among Selected Patients with Suspected Sepsis: The DETOURS Trial
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S-EPMC8643792 | biostudies-literature
TranscriptomicsMethamphetamine administration causes differential alterations in gene expression and dynamic patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens
Methamphetamine (METH) addiction is associated with a plethora of neuropsychiatric symptoms. In rodents, administration of the drug is accompanied by complex changes in gene expression in the dorsal striatum. Very little is known about the effects of the drug on gene expression and epigenetic modifi...
ORGANISM(S): Rattus norvegicus 
2011-07-31 | E-GEOD-31081 | biostudies-arrayexpress
GenomicsGenome-wide analysis of acetylated H4K5 binding offers new insights into the acute and chronic effects of METH on gene expression in the dorsal striatum
In contrast to the acute METH-induced transcriptional changes, chronic METH administration produces differential changes in IEG responses and blunts the striatal effects of a single METH injection (McCoy et al., 2011). These observations suggested that chromic METH might have caused changes in the m...
ORGANISM(S): Rattus norvegicus 
2013-02-28 | E-GEOD-42776 | biostudies-arrayexpress
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