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Nuclear pore complexes (NPCs) enable nucleocytoplasmic transport. While NPCs primarily localize to the nuclear envelope (NE), they also appear in cytoplasmic endoplasmic reticulum (ER) membranes called annulate lamellae (AL). Though discovered in the mid-20th century, AL’s function and biogenesis re...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD073946 | Pride
Activation of the transforming growth factor β (TGF-β) signaling leads to established hallmarks of cancer such as the epithelial-to-mesenchymal transition (EMT), initiating cancer dissemination and increasing chemoresistance. TGF-β signal by binding to its type I and II receptors, leading to paralle...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD057186 | Pride
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