Sort   by:  
 Page size 
TranscriptomicsPrionic protein gene dosage is critical for maintenance of neuronal homeostasis of hippocampal circuits
We demonstrate that Prnp dosage is critical for the maintenance of neuronal homeostasis since both its absence and, more relevantly, its overexpression induce higher sensitivity to kainate (KA) damage. These data correlate with electrophysiological results in freely behaving mutant mice showing an i...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-16223 | biostudies-arrayexpress
TranscriptomicsGene expression in response to axotomy in organotypical slices co-cultures
Brain slice cultures offer advantages over other in vitro methods, as they mimic numerous in vivo aspects. For most purposes, slices of the developing brain, termed organotypic slice cultures , preserve a high degree of cellular differentiation and tissue organization. The entorhino-hippocampal conn...
ORGANISM(S): Rattus norvegicus 
2011-02-25 | E-GEOD-20528 | biostudies-arrayexpress
TranscriptomicsGene expression profile associated with the PDZ ligand-motif of HPV16-E6 oncoprotin in the skin of transgenic mice models
The K14E6 transgenic mice developskin hyperplasia,benign tumors and skin cancer. The tumor formation capacity diminishes when E6 lacks its PDZ ligand-motif. This study aims to compare the transciptional profiles of transgenic K14E6 mice with K14E6 Δ146-151 (lacking the PDZ domain) in order to explor...
ORGANISM(S): Mus musculus 
2010-07-27 | E-GEOD-22417 | biostudies-arrayexpress
UnknownColombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery - a prospective cohort study.
Not available
S-EPMC11382124 | biostudies-literature
Sort   by:  
 Page size