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TranscriptomicsMithramycin Depletes Sp1 and Activates p53 to Mediate Senescence and Apoptosis of Pleural Mesothelioma Cells
We used microarrays to detail the global gene expression of mithramycin treated cells, xenografts and sp1 depleted cells with p53 overexpression. MPM cells and xenografts were treated with mithramycin or SP1 depleted/p53 overexpressed MPM cells were selected for RNA extraction and hybridization on A...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-64738 | biostudies-arrayexpress
TranscriptomicsExpression data analyzing ID3 (Inhibitor of DNA binding 3)-affected mouse T cells
Mouse CD8+ T cells affected by ID3 (Inhibitor of DNA binding 3) display patterns of gene expression suggesting enhanced persistance and survival. In this study, we identified genes differentially expressed between ID32a transduced and mock transduced, and ID32a knockout and wild type mouse CD8+ T ce...
ORGANISM(S): Mus musculus 
2011-10-15 | E-GEOD-23568 | biostudies-arrayexpress
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