Rat cardiac tissue

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Transcriptomics (867)
Unknown (737)
Genomics (127)
Proteomics (81)
Metabolomics (21)

Organisms

Rattus norvegicus (329)
Mus musculus (239)
Homo sapiens (168)
Rattus rattus (29)
Bos taurus (11)
Sus scrofa (10)
Drosophila melanogaster (10)
Danio rerio (10)
Gallus gallus (7)
Colinus virginianus (5)
Arabidopsis thaliana (5)
Macaca mulatta (4)
Rousettus aegyptiacus (3)
Oncorhynchus mykiss (3)
Bathyergus suillus (2)
Brugia pahangi (2)
Mus musculus domesticus (2)
mixed sample (2)
Heterocephalus glaber (2)
Plasmodium falciparum (2)
Canis lupus familiaris (2)
Cryptomys hottentotus hottentotus (1)
Spalax carmeli (1)
Larimichthys crocea (1)
Streptococcus dysgalactiae subsp. equisimilis (1)
Saccharum sp. (1)
Chenopodium amaranticolor (1)
Boehmeria nivea (1)
Cucumis sativus var. sativus (1)
Vibrio cholerae O1 biovar El Tor str. N16961 (1)

Organisms

Rattus norvegicus (64)
Mus musculus (9)
Homo sapiens (7)
Rattus rattus (1)
Sus scrofa (1)

Repository

biostudies-arrayexpress (836)
ENA (104)
geo (57)
pride (45)
MetaboLights (21)
MassIVE (19)
iProX (8)
jPOST (3)
PanoramaPublic (2)
PAXDB (2)
EGA (1)

Tissue

Heart (36)
Cardiac muscle cell (6)
Cell culture (3)
Cardiac muscle tissue of ventricle (2)
Cardiocyte (2)
Blood plasma (1)
Cardiac muscle (1)
Cardiac muscle myoblast (1)
Cardiac muscle tissue (1)
Cardiomyocyte cell line (1)
Colon (1)
Diaphragm (1)
Heart left ventricle (1)
Heart ventricle (1)
Microglial cell (1)
Regular cardiac myocyte (1)
Skeletal muscle tissue (1)
Stem cell (1)
Urine (1)

Disease

Cardiovascular system disease (9)
Normal (8)
Myocardial ischemia (7)
Hypertension (2)
Type 2 diabetes mellitus (2)
GIP-dependent Cushing's syndrome (1)
Osteosarcoma subtype fibroblastic (1)
Primary effusion lymphoma (PEL) (1)
Model of metabolic syndrome (1)
Ischaemia reperfusion injury (1)
Pneumococcal meningitis (1)
Schizophrenia (1)
Sham surgery (1)
Reference (1)
Breast cancer (1)
Cardiomyopathy (1)
Chronic kidney disease (1)
Diaphragm disease (1)
Heart disease (1)
Myocardial infarction (1)
Prostate cancer (1)

Technology Type

Mass Spectrometry (45)
Shotgun proteomics (33)
Mass spectrometry (16)
Bottom-up proteomics (8)
Data-dependent acquisition (6)
Affinity purification coupled with mass spectrometry proteomics (4)
Mass spectrometry assay (3)
Gel-based experiment (3)
NMR spectroscopy (2)
Top-down proteomics (2)
Mass spectrometry imaging (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (38)
Illumina HiSeq 4000 (16)
NextSeq 500 (15)
Illumina HiSeq 2000 (10)
Illumina HiSeq 2500 (9)
NextSeq 550 (6)
NextSeq 2000 (5)
Agilent High resolution C scanner (4)
DNBSEQ-G400 (3)
10x Chromium Controller (2)
The Agilent scanner G2565BA (2)
Agilent�s Microarray Hybridization Oven (2)
NanoDrop ND-1000 Spectrophotometer (NanoDrop Technologies) (2)
DNBSEQ-G400 FAST (1)
10X Genomics Chromium v3.1 with multiplexing kit (1)
Diva (1)
PromethION (1)
MA900, Sony (1)
Computer and Applied Biosystems 7500 Real Time PCR Systems thermal cycler (1)
Illumina TruSeq (1)
Axon Instruments GenePix 4000B scanner (1)
Solexa 2G Genome Analyzer (1)
PacBio RS II (1)
428 [Affymetrix] (1)
Scanning hardware (1)
Sony SH800S (1)
Illumina NovaSeq X (1)
N/A (1)
HiSeq X Ten (1)
Illumina HiSeq 3000 (1)

Publication Date

2010 (108)
2015 (87)
2014 (86)
2012 (76)
2011 (75)
2013 (70)
2008 (51)
2005 (48)
2016 (47)
2024 (42)
2009 (41)
2026 (39)
2007 (33)
2022 (30)
2023 (27)
2018 (23)
2020 (21)
2025 (20)
2021 (20)
2006 (16)
2019 (13)
2017 (9)
2004 (1)
2003 (1)

UNIPROT ID/AC

9544.ENSMMUP00000000273 (2)
9544.ENSMMUP00000000423 (2)
9544.ENSMMUP00000000529 (2)
9544.ENSMMUP00000000740 (2)
9544.ENSMMUP00000000801 (2)
9544.ENSMMUP00000000905 (2)
9544.ENSMMUP00000001049 (2)
9544.ENSMMUP00000001128 (2)
9544.ENSMMUP00000001205 (2)
9544.ENSMMUP00000001234 (2)
9544.ENSMMUP00000001377 (2)
9544.ENSMMUP00000001480 (2)
9544.ENSMMUP00000001594 (2)
9544.ENSMMUP00000001769 (2)
9544.ENSMMUP00000001808 (2)
9544.ENSMMUP00000001915 (2)
9544.ENSMMUP00000001927 (2)
9544.ENSMMUP00000001935 (2)
9544.ENSMMUP00000002100 (2)
9544.ENSMMUP00000002322 (2)
9544.ENSMMUP00000002527 (2)
9544.ENSMMUP00000002550 (2)
9544.ENSMMUP00000002611 (2)
9544.ENSMMUP00000002781 (2)
9544.ENSMMUP00000002941 (2)
9544.ENSMMUP00000003002 (2)
9544.ENSMMUP00000003176 (2)
9544.ENSMMUP00000003469 (2)
9544.ENSMMUP00000003585 (2)
9544.ENSMMUP00000003611 (2)

CHEBI ID

CHEBI:16737 (11)
CHEBI:28044 (10)
CHEBI:15891 (10)
CHEBI:16027 (10)
CHEBI:27897 (10)
CHEBI:30769 (10)
CHEBI:18237 (9)
CHEBI:22660 (9)
CHEBI:22653 (9)
CHEBI:16811 (9)
CHEBI:28300 (9)
CHEBI:15741 (9)
CHEBI:17154 (9)
CHEBI:27266 (9)
CHEBI:17750 (9)
CHEBI:16704 (9)
CHEBI:16919 (9)
CHEBI:17368 (9)
CHEBI:33508 (8)
CHEBI:17822 (8)
CHEBI:16680 (8)
CHEBI:26271 (8)
CHEBI:25094 (8)
CHEBI:17858 (8)
CHEBI:17126 (8)
CHEBI:27570 (8)
CHEBI:18186 (8)
CHEBI:18257 (8)
CHEBI:16708 (8)
CHEBI:25017 (8)

Metabolite Name

Creatinine (7)
Taurine (6)
Hypoxanthine (6)
Malate (5)
Aspartate (5)
Ornithine (5)
Asparagine (5)
Threonine (5)
Succinate (5)
Proline (5)
Citrate (5)
Xanthine (5)
Creatine (5)
Tryptophan (5)
Glucose-6-phosphate (4)
Fructose-6-phosphate (4)
Glutamate (4)
Leucine (4)
Valine (4)
Betaine (4)
Methionine (4)
Arginine (4)
Lysine (4)
Serine (4)
Adenosine (4)
Phosphocreatine (4)
Isoleucine (4)
Glutamine (4)
Glucose (4)
Cytidine (4)

First Public Date

2014 (18)
2024 (17)
2026 (13)
2023 (9)
2022 (9)
2025 (8)
2021 (6)
2020 (6)
2019 (6)
2018 (6)
2015 (4)
2017 (1)
2016 (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (574)
RNA-seq of coding RNA (103)
RNA-seq of coding RNA from single cells (38)
RNA-seq of non coding RNA (21)
Unknown experiment type (16)
ChIP-seq (10)
Other (9)
Comparative genomic hybridization by array (7)
Methylation profiling by array (6)
Animal - One-color microarray (5)
Genotyping by array (5)
RNA-seq of total RNA (5)
Transcription profiling by tiling array (3)
Transcription profiling by RT-PCR (3)
MicroRNA profiling by high throughput sequencing (3)
ATAC-seq (3)
Methylation profiling by high throughput sequencing (3)
Transcription profiling by SAGE (2)
Cell line - One-color microarray (2)
ScATAC-seq (2)
MicroRNA profiling by array (2)
DNA-seq (2)
Differential (1)
ChIP-chip by tiling array (1)
Animal - Single-cell sequencing (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Proteomic profiling by mass spectrometer (1)
ChIP-chip by array (1)
CLIP-seq (1)

Release Date

2010 (117)
2015 (115)
2014 (107)
2023 (100)
2012 (91)
2011 (91)
2022 (90)
2021 (88)
2013 (87)
2020 (75)
2025 (66)
2024 (65)
2016 (65)
2019 (63)
2008 (57)
2018 (56)
2009 (50)
2005 (50)
2017 (45)
2007 (37)
2026 (34)
2006 (17)
2004 (2)
1999 (2)
2003 (1)
2001 (1)
1998 (1)

Lab affiliation

Department of Thoracic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650000, Yunnan, China. (2)
Executive Science Officer, BioFrontiers InstituteDistinguished ProfessorProfessor, Howard Hughes Medical Institute MOLECULAR CELLULAR AND DEVELOPMENTAL BIOLOGY CU DENVER SCHOOL OF MEDICINE (2)
Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Maastricht, The Netherlands (2)
Proteomics Core Facility, Sahlgrenska Academy, University of Gothenburg, Sweden (2)
Angiogenesis Laboratory, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Lisbon School of Medicine of the Universidade de Lisboa; Lisbon, 1649-028, Portugal (1)
Assistant Professor of Microbiology, Immunology, and Cancer Biology Associate Director for Diversity, Equity, and Inclusio at the Carter Immunology Center University of Virginia Charlottesville, VA (1)
Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA (1)
Cedars-Sinai Medical Center (1)
Cedars-Sinai Medical Center Advanced Clinical Biosystems Research Institute Advanced Health Science Pavillion, Room A9307 8700 Beverly Blvd. Los Angeles, CA 90048 (1)
Charles Perkins Centre, University of Sydney (1)
Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China (1)
Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada; Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada; The Hotchkiss Brain Institute, University of Calgary, Alberta, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada (1)
Department of Biomedical Sciences, Affiliated with The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen. (1)
Department of Cardiology, Medical University Hospital, Heidelberg, Germany (1)
Department of Cell and Regenerative Biology, Department of Chemistry, University of Wisconsin-Madison (1)
Department of Forensic Medicine, Faculty of Basic Medical Sciences, Chongqing Medical University (1)
Department of Integration of Chinese and Western Medicine, School of Basic Medicine Science, Peking University, China (1)
Department of Internal Medicine, Botucatu Medical School, São Paulo State University, UNESP, SP, Brazil (1)
Department of Medical Sciences iBiMED University of Aveiro (1)
Department of Medical Sciences, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates and/or Department of Physiological Sciences, College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia. (1)
Department of Molecular Cell Biology Weizmann Institute of Science (1)
Department of Molecular and Clinical Medicine, Institueof Medicine,Sahlgrenska Academy at Gothenburg University (1)
Director, Advanced Clinical Biosystems Research Institute, Cedars-Sinai Medical Center (1)
Discovery Proteomics Facility University of Oxford (1)
Emory University School of Medicine Departments of Biochemistry and Neurology (1)
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland, and Department of Cardiothoracic Surgery, Jena University Hospital, Jena, Germany (1)
HUN-REN–SU System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Pharmahungary Group, Záhony utca 7, 1031 Budapest, Hungary (1)
Institue of Physiology II, University of Münster, Münster, Germany (1)
J. Craig Venter Institute, Rockville, MD 20850 (1)
Laboratory of Mass Spectrometry Institute of Bioorganic Chemistry Polish Academy of Sciences Poznan, Poland (1)

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Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...

2021-12-08 | MTBLS3174 | MetaboLights

Transcription profiling of rat heterotopic cardiac transplants

Heterotopic cardiac transplants were constructed in male Wistar Furth (allograft donor) and ACI (host) rats. Rats were divided into three groups consisting of no treatment, treatment with a sub-therapeutic dose of cyclosporin A, and treated with combination of a sub-therapeutic dose of cyclosporin A...

ORGANISM(S): Rattus norvegicus

2009-11-28 | E-GEOD-15074 | biostudies-arrayexpress

Transcription profiling of normal adult rat extraocular muscle, cardiac muscle, leg (gastrocnemius-soleus) muscle and smooth muscle (stomach wall)

Comparison of normal adult rat extraocular muscle, cardiac muscle, leg (gastrocnemius-soleus) muscle and smooth muscle (stomach wall). Affymetrix microarray chip RG-U34A was used. MAS version 5 was used to analyze the muscle group differences. Data form part of publication: FASEB Journal 17: 1370-...

ORGANISM(S): Rattus norvegicus

2007-10-27 | E-GEOD-142 | biostudies-arrayexpress

LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets (Rat cardiomyocyte assay)

Lipids are dynamic constituents of biological systems, rapidly responding to any changes in physiological conditions. Thus, there is a large interest in lipid-derived markers for diagnostic and prognostic applications, especially in translational and systems medicine research. As lipid identificatio...

2018-07-31 | MTBLS483 | MetaboLights

intracellular MMP-2 proteolysis in cardiac tissue

Induced proteolysis of rat heart extracts with recombinant MMP-2 followed by subtiligase-N-terminomics

ORGANISM(S): Rattus (ncbitaxon:10114)

2023-11-01 | MSV000093229 | MassIVE

In-depth quantitative proteomic analysis of rat cardiac tissue for exploring potential mediators of early cardiac reaioablation effect

Recently, stereotactic ablative radiotherapy (SABR) is adopted to noninvasively treat catheter ablation-refractory ventricular tachycardia (VT). VT episodes were dramatically reduced after SABR within few weeks, but underlying mechanisms of these clinical effects as well as potential mediator of ear...

ORGANISM(S): Rattus norvegicus (Rat)

2022-08-12 | PXD030878 | Pride

An RNASeq normal tissue atlas for mouse and rat

The function of a gene is closely connected to its expression specificity across tissues and cell types. RNA-Seq is a powerful quantitative tool to explore genome wide expression. The aim of the present study is to provide a comprehensive RNA-Seq dataset across the same 13 tissues for mouse and rat,...

ORGANISM(S): Rattus norvegicus

2017-10-25 | E-MTAB-6081 | biostudies-arrayexpress

Immortalized cardiac cell line characterization and comparison (rat/rat-derived)

The aim of this study was to compare the most common immortalized cardiac cell lines (human: AC16, rat: H9C2, mouse: HL-1) to primary cultures (neonatal rat or mouse cardiomyocytes, and human induced pluripotent stem cells) and left ventricular tissues from the corresponding species. To characterize...

ORGANISM(S): Rattus norvegicus

2022-01-04 | E-MTAB-10913 | biostudies-arrayexpress

Expression data from rat urinary bladder and non-glandular stomach tissue samples

Seven novel and potent Raf small molecule kinase inhibitors were evaluated in 7-day oral repeat-dose rat toxicity studies. All compounds tested induced hyperplasia in multiple tissues. Microarrays were used to investigate transciptional changes associated by treatment with a single compound to gain ...

ORGANISM(S): Rattus norvegicus

2011-07-18 | E-GEOD-26936 | biostudies-arrayexpress

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