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TranscriptomicsTranscriptome Sequencing (RNA-seq) of Ara-C Resistant Murine AML Cell Lines Identifies Mechanisms of Resistance
An RNA-seq study of altered gene expression and mutations in Ara-C resistant acute myeloid leukemia murine cell lines. The analysis of the RNA-seq data led to the identification of a large deletion within the Dck coding sequence of the B117H cell line, which produced an alternatively processed form...
ORGANISM(S): Mus musculus 
2014-08-13 | E-GEOD-47454 | biostudies-arrayexpress
TranscriptomicsNRASG12V mediates self renewal in AML [RNA-Seq]
Mutant RAS oncoproteins activate signaling molecules that drive oncogenesis in multiple human tumors including acute myelogenous leukemia (AML). However, the specific function of these pathways in AML is unclear. To elucidate the downstream functions of activated NRAS in AML, we employed a murine mo...
ORGANISM(S): Mus musculus 
2014-11-16 | E-GEOD-49087 | biostudies-arrayexpress
UnknownProliferation and Self-Renewal Are Differentially Sensitive to NRASG12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line.
Not available
S-EPMC9633370 | biostudies-literature
TranscriptomicsNRASG12V oncogene mediates self-renewal in acute myelogenous leukemia
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-11-16 | E-GEOD-49089 | biostudies-arrayexpress
UnknownPolypill with or without Aspirin in Persons without Cardiovascular Disease.
Not available
S-EPMC7116860 | biostudies-literature
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