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TranscriptomicsComparison of gene expression in wild-type Drosophila testes with tbrd-1 mutant testes
Gene expression is tightly linked to histone acetylation on lysine residues that can be recognized by bromodomains. The testis-specific bromodomain protein tBRD-1 is essential for male fertility and might act as a co-factor of testis-specifc TAFs. Here, we perform microarray analyses and demonstrate...
ORGANISM(S): Drosophila melanogaster 
2014-08-08 | E-GEOD-52511 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Drosophila melanogaster testis with or without tbrd-1 knock out or tplus3a/b knock out
Many protein complexes are involved in gene regulation during Drosophila spermatogenesis. tplus3a and tplus3b code for Plus3 domain proteins and are enriched in spermatocytes. Male flies ∆tplus3a/b carrying deletions of both genes in trans to deficiency Df(2L)BSC151 show severely reduced fertility. ...
ORGANISM(S): Drosophila melanogaster 
2019-11-04 | E-MTAB-7013 | biostudies-arrayexpress
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