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TranscriptomicsMethylation profiling of lung squamous cell carcinomas vs surrounding normal tissue
Methylated genomic fragments from tumor and matching normal DNA were enriched with the methylated-CpG island recovery assay (MIRA); amplified, labeled and hybridized on Agilent CpG island tiling oligo arrays. Samples from tumor were labeled with Cy5 while the matching normal were labeled with Cy3 so...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-9622 | biostudies-arrayexpress
TranscriptomicsGlobal methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders
Autism is currently considered a multigene disorder with epigenetic influences. To investigate the contribution of DNA methylation to autism spectrum disorders, we have recently completed large-scale methylation profiling by CpG island microarray analysis of lymphoblastoid cell lines (LCL) derived ...
ORGANISM(S): Homo sapiens 
2010-04-27 | E-GEOD-21395 | biostudies-arrayexpress
TranscriptomicsDNA methylation in B cells
Using a methylated-DNA enrichment technique (MIRA) in combination with whole genome tiling arrays, we have characterized by MIRA-chip the entire B cell ‘methylome’ of an individual human at 100 base pair resolution. Methylated fragments in genomic DNA extracted from B cells were enriched with the M...
ORGANISM(S): Homo sapiens 
2008-12-31 | E-GEOD-13700 | biostudies-arrayexpress
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