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ProteomicsComaprison of the phagosome proteome of bone marrow-derived macrophages and RAW264.7
Macrophages are important immune cells operating at the forefront of innate immunity by taking up foreign particles and microbes through phagocytosis. The RAW 264.7 cell line is commonly used for experiments in the macrophage and phagocytosis field. However, little is known how its functions compare...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084938 | MassIVE
TranscriptomicsTranscription profiling of mouse triplicate samples of RAW 264.7 murine macrophages either untreated, stimulated with 100 ng/ml LPS for 18 hours, or constituitively over-expressing CstF-64
Triplicate samples of RAW 264.7 murine macrophages either untreated, stimulated with 100 ng/ml LPS for 18 hours, or constituitively over-expressing CstF-64 were analyzed by microarray using Affymetrix murine gene chip 430A.
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-2002 | biostudies-arrayexpress
TranscriptomicsExpression data from LPS-stimulated RAW 264.7 mouse macrophages treated with Hypericum perforatum fraction and bioactive constituents
Hypericum perforatum extracts have been used as dietary supplements to treat conditions including mild-moderate depression and inflammation. A group of four bioactive constituents were identified from an active fraction of the extract. In order to identify the mechanism for the potential anti-inflam...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21841 | biostudies-arrayexpress
OtherHigh-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages.
Data from ProteomeXchange, PXD ID: PXD001293. File: BMDM_2.mzml. Published as part of Proteomics. 2014 Dec 12 . From the Abstract: {{i}} Macrophages are important immune cells operating at the forefront of innate immunity by taking up foreign particles and microbes through phagocytosis. The RAW 264...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320007638 | GPMDB
Resource Reanalysis 
TranscriptomicsExpression data from BNL CL.2 liver cells when cultured with iron, RAW 264.7 macrophages or both
We found that co-culturing BNL CL.2 liver cells with RAW 264.7 macrophages increased IRP binding in the first. To further investigate this modulation we investigated the gene expression profile in BNL CL.2 cells cultured alone, with iron, with RAW 264.7 macrophages or in the presence of both iron an...
ORGANISM(S): Mus musculus 
2016-10-22 | E-GEOD-32090 | biostudies-arrayexpress
TranscriptomicsExpression data from RAW 264.7 macrophage
IFNg is a pro-inflammatory and pro-atherogenic cytokine that leads to macrophage activation. Adenosine has well-documented anti-inflammatory properties. We used microarrays to compare the global gene expression profile in mouse macrophages stimulated with IFNg alone and those cells treated with IFNg...
ORGANISM(S): Mus musculus 
2009-12-30 | E-GEOD-14612 | biostudies-arrayexpress
TranscriptomicsEffect of LPS and LPS-binding protein treatment on RAW 264.4 cells
All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RA...
ORGANISM(S): Mus musculus 
2004-03-04 | E-GEOD-1098 | biostudies-arrayexpress
TranscriptomicsSynergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A.
Tumor-associated macrophages (TAMs) represent alternatively activated (M2) macrophages that support tumor growth. Previously, we have described a special LYVE-1(+) M2 TAM subset in vitro and in vivo; gene profiling of this TAM subset identified MS4A8A as a novel TAM molecule expressed in vivo by TAM...
ORGANISM(S): Mus musculus 
2012-05-22 | E-GEOD-38171 | biostudies-arrayexpress
TranscriptomicsLPS stimulation of Mouse (RAW 264.7) macrophages
Immunoresponsive gene 1 (IRG1) is one of the highest induced genes in macrophages under pro-inflammatory conditions and its function has been recently described: it codes for immune-responsive gene 1 protein/cis-aconitic acid decarboxylase (IRG1/CAD), an enzyme catalyzing the production of itaconic ...
ORGANISM(S): Mus musculus 
2016-02-25 | E-GEOD-76562 | biostudies-arrayexpress
TranscriptomicsGene expression and synergistic interactions induced by CpG ODN and/or poly(I:C)
Bioinformatic analysis of microarray data was used to identify the regulatory patterns underlying changes in gene expression induced when RAW 264.7 macrophages were stimulated via TLR9 by CpG oligonucleotides (ODN) and/or via TLR3 by poly (I:C). While the genes activated by each ligand mediated simi...
ORGANISM(S): Mus musculus 
2009-07-21 | E-GEOD-15416 | biostudies-arrayexpress
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