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TranscriptomicsGene expression analysis of T-ALL cell lines treated with gamma-secretase inhibitor
Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising target for drugs such as gamma-secretase inhibitors (GSI), which block a proteolytic cleavage required for NOTCH1 activation. However, the enthusiasm for these therapies has been temper...
ORGANISM(S): Homo sapiens 
2008-08-20 | E-GEOD-5716 | biostudies-arrayexpress
TranscriptomicsMice cerbellum extracts: SCA7 KI mice vs. wild type mice
Transcriptional profiling of mouse cerebellar extract comparing SCA7 KI mice with wild type mice. Female mice were killed by decapitation on post natal days 10 and 22 and 11 weeks. Goal was to determine gene expression profiles differing between SCA7 KI mice and wild-type mice during post-natal deve...
ORGANISM(S): Mus musculus 
2013-07-24 | E-GEOD-49115 | biostudies-arrayexpress
UnknownSevere and multiple hypoglycemic episodes are associated with increased risk of death in ICU patients.
Not available
S-EPMC4470320 | biostudies-literature
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