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TranscriptomicsMLL2 facilitates long-range gene regulation through LINE1 elements [Micro-C]
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 deposition at bivalent promoters, which has been proposed to facilitate the induction of major develo...
ORGANISM(S): Mus musculus 
2025-10-23 | E-MTAB-15688 | biostudies-arrayexpress
ProteomicsProteogenomic characterization of human colon and rectal cancer
Explore This Study at the NCI Proteomic Data Commons

Zhang, B., et al., Nature (2014) do...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-26 | MSV000084238 | MassIVE
UnknownRapid scan EPR: Automated digital resonator control for low-latency data acquisition.
Not available
S-EPMC10266206 | biostudies-literature
GenomicsBromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (ChIP-Seq)
Pharmacological inhibition of chromatin co-regulatory factors represents a clinically validated strategy to modulate oncogenic signaling through selective attenuation of gene expression. Here, we demonstrate that CBP/EP300 bromodomain inhibition preferentially abrogates the viability of multiple mye...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-71909 | biostudies-arrayexpress
MetabolomicsHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...
2018-02-12 | MTBLS452 | MetaboLights
TranscriptomicsAerobic and anaerobic transcriptional responses of wild type, hmp and norR to strains to NO in a chemostat
This SuperSeries is composed of the following subset Series: GSE5075: Aerobic transcriptional responses of Escherichia coli to NO under defined chemostat conditions. GSE5076: Anaerobic transcriptional responses of Escherichia coli to NO under defined chemostat conditions. GSE5084: Anaerobic NO-expos...
ORGANISM(S): Escherichia coli 
2006-08-31 | E-GEOD-5098 | biostudies-arrayexpress
TranscriptomicsAerobic NO-exposed Chemostat Comparison of Wt & norR mutant Responses
Escherichia coli strains MG1655 and an isogenic norR::Tn5 mutant were grown in a New Brunswick Scientific Bioflow III Biofermentor under continuous culture (chemostat) conditions.. Cells were grown in defined media containing 8 mM glycerol as the sole and limiting source of energy and carbon. The wo...
ORGANISM(S): Escherichia coli 
2006-08-31 | E-GEOD-5137 | biostudies-arrayexpress
TranscriptomicsAerobic NO-exposed Chemostat Comparison of Wt & hmp mutant Responses
Escherichia coli strains MG1655 and an isogenic hmp::Tn5 mutant were grown in a New Brunswick Scientific Bioflow III Biofermentor under continuous culture (chemostat) conditions.. Cells were grown in defined media containing 8 mM glycerol as the sole and limiting source of energy and carbon. The wor...
ORGANISM(S): Escherichia coli 
2006-08-31 | E-GEOD-5139 | biostudies-arrayexpress
TranscriptomicsAerobic transcriptional responses of Escherichia coli to NO under defined chemostat conditions.
Escherichia coli strain MG1655 was grown in a New Brunswick Scientific Bioflow III Biofermentor under continuous culture (chemostat) conditions. Cells were grown in defined media containing 8 mM glycerol as the sole and limiting source of energy and carbon. The working volume was 1 litre, and the ...
ORGANISM(S): Escherichia coli 
2010-07-01 | E-GEOD-5075 | biostudies-arrayexpress
TranscriptomicsAnaerobic transcriptional responses of Escherichia coli to NO under defined chemostat conditions.
Escherichia coli strain MG1655 was grown in a New Brunswick Scientific Bioflow III Biofermentor under continuous culture (chemostat) conditions. Cells were grown in defined media containing 54 mM glycerol as the sole and limiting source of energy and carbon. The working volume was 1 litre, and the d...
ORGANISM(S): Escherichia coli 
2010-07-01 | E-GEOD-5076 | biostudies-arrayexpress
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