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UnknownApelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms.
Not available
S-EPMC3033059 | biostudies-literature
TranscriptomicsBilberries reduce low-grade inflammation and subacute endotoxemia in individuals with features of metabolic syndrome - microarray/QPCR profiling of dietary effects of bilberries in PBMCs
Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. The most diverse source of dietary anti-inflammatory compounds is polyphenols and especially anthocyanins, which are major polyphenols in bilberries (Vaccinium myrtillus). We investigated the effec...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-34145 | biostudies-arrayexpress
TranscriptomicsNutritional programming of the metabolic syndrome is associated with long-lasting changes in nutrient sensing and energy homeostasis in the hypothalamus as revealed by genome-wide DNA microarray analysis
Nutrient deficiency during perinatal development is associated with an increased risk to develop obesity, diabetes and hypertension in adulthood. However, the molecular mechanisms underlying the developmental programming of the metabolic syndrome remain largely unknown. Given the essential role of t...
ORGANISM(S): Rattus norvegicus 
2010-07-02 | E-GEOD-22540 | biostudies-arrayexpress
UnknownAdvanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Not available
S-EPMC5360279 | biostudies-literature
TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (old mouse liver)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43173 | biostudies-arrayexpress
TranscriptomicsCommon pathways involved in adipose tissue inflammation and atherosclerosis
Adipose tissue inflammation and atherosclerosis are the main mechanisms behind type 2 diabetes and cardiovascular disease respectively, the major risks associated with the metabolic syndrome. Studies considering more than single factors behind the complexity of the metabolic syndrome are valuable to...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-76812 | biostudies-arrayexpress
TranscriptomicsMetabolic syndrome exercise training
We assessed vastus lateralis muscle gene expression levels of 12 women with the metabolic syndrome before and after a 6 month exercise training program RNA was isolated from a vastus lateralis muscle biopsy of 6 women with the metabolic syndrome before and after a 6 month guided endurance exercise t...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-43760 | biostudies-arrayexpress
TranscriptomicsGenetic regulation of human adipose microRNA expression and its consequences for metabolic traits
The genetics of messenger RNA expression has been extensively studied in humans and other organisms, but little is known about genetic factors contributing to microRNA (miRNA) expression. We examined natural variation of miRNA expression in adipose tissue in a population of 200 men who have been car...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-45159 | biostudies-arrayexpress
TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (young mouse liver)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43171 | biostudies-arrayexpress
TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (young mouse white fat)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43172 | biostudies-arrayexpress
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