Sort   by:  
 Page size 
TranscriptomicsMethod Study
High-throughput sequencing (HTS) of antibody amplicon libraries has become a powerful method in the emerging field of systems immunology. However, numerous sources of bias in HTS workflows may affect antibody repertoire data. A crucial step in antibody amplicon library preparation is the addition of...
ORGANISM(S): Mus musculus 
2014-02-20 | E-MTAB-2226 | biostudies-arrayexpress
TranscriptomicsCXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AHR signaling
Targeting the estrogen signaling pathway has proved to be of great value in the treatment of human breast cancer. Tamoxifen, a selective estrogen receptor modulator (SERM), is the most widely used antiestrogen. However, only 40-50% of patients with estrogen receptor (ER) positive breast cancer benef...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-31831 | biostudies-arrayexpress
TranscriptomicsTranscriptomics of Axillary Bud Outgrowth Regulation by Shade Signals in Arabidopsis
Aims: To determine the changes in the Arabidopsis axillary bud transcriptome in response to changes in the red light (R) to far red light (FR) ratio (R:FR). Background: The branching habit of plants is a key determinant of overall plant form and function with great relevance to modern agriculture. S...
ORGANISM(S): Arabidopsis thaliana 
2012-11-21 | E-GEOD-42415 | biostudies-arrayexpress
UnknownEvaluation of Effectiveness and Tolerability of Fondaparinux in the Management of Symptomatic Acute Coronary Syndrome: A Real-World Evidence-Based Study on an Indian Population.
Not available
S-EPMC8933594 | biostudies-literature
TranscriptomicsTranscritpome analysis of Mycobacterium tuberculosis (Mtb) mutants deficient in ergothioneine, or mycothiol production
This experiment was performed to determine deferentially regulated genes in the absence of redox buffer ergothioneine (EGT), or mycothiol (MSH). We had used two Mtb mutants namely egtA:Tn and egtD:Tn which are deficient in EGT production ( Transposon Mutant of EGT biosynthesis pathway); In additi...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2016-01-27 | E-MTAB-4099 | biostudies-arrayexpress
UnknownIdentification of ALKBH6 as a nucleotide demethylase with a distinct substrate preference.
Not available
S-EPMC12494543 | biostudies-literature
GenomicsBromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (ChIP-Seq)
Pharmacological inhibition of chromatin co-regulatory factors represents a clinically validated strategy to modulate oncogenic signaling through selective attenuation of gene expression. Here, we demonstrate that CBP/EP300 bromodomain inhibition preferentially abrogates the viability of multiple mye...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-71909 | biostudies-arrayexpress
TranscriptomicsEffect of Ovarian Hormone on Gene Expression in Rhesus Dorsal Raphe Nucleus with Human U95A Affymetrix Chip
Small blocks of the midbrain containing the dorsal raphe nucleus was obtained from ovariectomized monkeys treated with placebo, estrogen, progesterone or estrogen plus progesterone for one month. The RNA was extracted and hybridized to the human U95A Affymetrix chip. Each chip represents one monkey....
ORGANISM(S): Macaca mulatta 
2009-05-21 | E-GEOD-16171 | biostudies-arrayexpress
ProteomicsA cullin-RING ubiquitin ligase promotes thermotolerance as part of the Intracellular Pathogen Response in C. elegans.
Intracellular pathogen infection leads to proteotoxic stress in host organisms. Previously we described a physiological program in the nematode C. elegans called the Intracellular Pathogen Response (IPR), which promotes resistance to proteotoxic stress and appears to be distinct from canonical prote...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2020-02-07 | MSV000084936 | MassIVE
UnknownEffectiveness and Tolerability of Fondaparinux vs Enoxaparin in a Population of Indian Patients with Symptomatic Deep Vein Thrombosis: A Retrospective Real-World Study.
Not available
S-EPMC8844336 | biostudies-literature
Sort   by:  
 Page size