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Regualtion of 5hMC during Twist-indced EMT
EMT is associated with profound epigenetic regualtion. 5hMC is the first product of TET-dependent DNA methylation product. chromatin immunoprecipitation-sequencing (ChIP-seq) provide a tool to define the changes of 5hmC at the genome level. Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for...
ORGANISM(S): Homo sapiens 
2023-03-16 | GSE227135 | GEO
Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regualtion
The functional roles of ANG, RNASE1, and AGO2 in the biogenesis and stablization regualtion of cellular and extracellular tDRs
This experiment was investigating how gut commensal bacteria and intestinal inflammation affect miRNA expression. We analyzed miRNA expression of spleen and intestine from specific pathogen free (SPF) B6 mice, germ-free (GF) B6 mice, and IL-10 knockout mice which have severe colitis by microarray. T...
ORGANISM(S): Mus musculus 
We report the application of the Illumina/Solexa sequencing-by-synthesis platform to identify microRNA, which invovled in bat hibernating regualtion, in brain and adipose tissue. Total 866 microRNAs (including 477 novels) were identified and 269 microRNAs showed significant expression differences du...
ORGANISM(S): Myotis pilosus 
2015-12-31 | GSE29053 | GEO
We report the application of the Illumina/Solexa sequencing-by-synthesis platform to identify microRNA, which invovled in bat hibernating regualtion, in brain and adipose tissue. Total 866 microRNAs (including 477 novels) were identified and 269 microRNAs showed significant expression differences du...
ORGANISM(S): Myotis ricketti 
Transcriptional profiling of Xanthomonas campestris pv. campestris 8004 comparing control wild type strain with ravA (or ravS or ravR) mutant The effects of mutating ravS, ravR and ravA on EPS synthesis, biofilm production and motility were very different , the factors responsible for these differe...
ORGANISM(S): Xanthomonas campestris pv. campestris 
Protein deacetylase SIRT6 and protein kinase ATM both decline during aging, which are of importance in regualtion of glucose metabolism . To explore the mechnisms of SIRT6 and ATM in glycolysis, we analysed the gene expressions in murine embryonic fibroblast cells generated from wildtype, Sirt6-/-, ...
ORGANISM(S): Mus musculus 
2018-05-05 | GSE109280 | GEO
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