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MetabolomicsCombined transcriptome and metabolome analysis reveals the regulatory network of histidine kinase QseC in the two-component system of Glaesserella parasuis
Glaesserella parasuis is the causative agent of Glässer's disease in pigs, which can lead to polyserositis, arthritis, and meningitis. This study used transcriptome and metabolomics sequencing techniques to investigate the mechanism of action of qseC gene in Glaesserella parasuis. Transmission elect...
2025-08-11 | MTBLS12504 | MetaboLights
MetabolomicsDelineating molecular regulatory network of meat quality of longissimus dorsi indicated by transcriptomic, proteomic, and metabolomics analysis in rabbit (UPLC-MS/MS assays)

This study aims to investigate the potential regulatory network responsible for the meat quality using multi-omics to help developing better varieties. Slaughter performance and meat quality of Shuxing No.1 rabbit outperformed Yila rabbit. Differentially expressed genes (DEGs) and differentially ...

2024-01-18 | MTBLS8957 | MetaboLights
MetabolomicsDelineating molecular regulatory network of meat quality of longissimus dorsi indicated by transcriptomic, proteomic, and metabolomics analysis in rabbit (SPME-GC-MS assay)

This study aims to investigate the potential regulatory network responsible for the meat quality using multi-omics to help developing better varieties. Slaughter performance and meat quality of Shuxing No.1 rabbit outperformed Yila rabbit. Differentially expressed genes (DEGs) and differentially ...

2024-01-18 | MTBLS8958 | MetaboLights
MetabolomicsMulti-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum

Tobacco is a significant industrial crop, serving as a model for plant science and a promising specie for the production of proteins and small molecules. However, system biology studies of tobacco under natural field cultivation conditions remain scarce. Here, we construct a genome-scale metaboli...

2025-09-30 | MTBLS13081 | MetaboLights
MetabolomicsMulti-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum

Tobacco is a significant industrial crop, serving as a model for plant science and a promising specie for the production of proteins and small molecules. However, system biology studies of tobacco under natural field cultivation conditions remain scarce. Here, we construct a genome-scale metaboli...

2025-09-29 | MTBLS13071 | MetaboLights
MetabolomicsMulti-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum

Tobacco is a significant industrial crop, serving as a model for plant science and a promising specie for the production of proteins and small molecules. However, system biology studies of tobacco under natural field cultivation conditions remain scarce. Here, we construct a genome-scale metabol...

2025-09-29 | MTBLS13072 | MetaboLights
MetabolomicsMulti-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum

Tobacco is a significant industrial crop, serving as a model for plant science and a promising specie for the production of proteins and small molecules. However, system biology studies of tobacco under natural field cultivation conditions remain scarce. Here, we construct a genome-scale metaboli...

2025-09-28 | MTBLS13060 | MetaboLights
MetabolomicsRegulatory actors and alternative routes for Arabidopsis seed germination are revealed using a pathway‐based analysis of transcriptomic datasets
Regulation of seed germination by dormancy relies on a complex network of transcriptional and post‐transcriptional modifications during seed imbibition that controls seed adaptive responses to environmental cues. High‐throughput technologies have brought significant progress in the understanding of ...
2019-05-21 | MTBLS662 | MetaboLights
MetabolomicsClinacanthus nutans fractions exert anti-nasopharyngeal carcinoma effects: integrating untargeted metabolomics, network pharmacology, molecular docking and experimental validation

Background: Clinacanthus nutans (C. nutans), a Southeast Asian medicinal herb, has ethnopharmacological potential against nasopharyngeal carcinoma (NPC). This study aimed to elucidate the bioactive compounds, potential molecular targets, and regulatory pathways responsible for the anticancer acti...

2026-01-05 | MTBLS13610 | MetaboLights
MetabolomicsIntegrated transcriptome and metabolome profiling unveils the tolerance network to potassium deficiency in wild soybean ecotypes

Facing the severe challenge of global soil potassium deficiency on crop production, two different ecological row types of wild soybean [ Glycine soja sieb. & Zucc. In order to reveal the physiological and molecular mechanisms of tolerance to low potassium stress in glycine soja, we compared t...

2025-07-22 | MTBLS12758 | MetaboLights
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