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TranscriptomicsExpression data from HeLa cells treated with RZ2
The newly sinthesized compound RZ2 induces cell death to human cancer cells. To obtain insights into its mechanism of action, the effects on autophagy and apoptosis were examined. Global perturbations in genome-wide RNA expression of HeLa cells treated with RZ2 were measured by gene expression micro...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-51948 | biostudies-arrayexpress
GenomicsdDsk2 stabilizes dHP1c binding at TSS [ChIP-Seq]
The Drosophila ubiquitin receptor dDsk2 associates to chromatin and stabilizes binding of the euchromatic dHP1c/WOC/ROW-complex (dHP1EU) to the transcription-start site (TSS) of active genes ChIP-Seq peak calling of WOC, ROW, Z4, HP1c and Dsk2 against Input sample in Drosophila melanogaster S2 cells
ORGANISM(S): Drosophila melanogaster 
2015-05-01 | E-GEOD-49102 | biostudies-arrayexpress
TranscriptomicsDrosophila ROW RNAi gene expression profiling
Heterochromatin-protein 1 (HP1) is a functionally diverse family of proteins. In particular, Drosophila dHP1c forms a complex with the transcription factors WOC and ROW (dHP1EU) that localizes at euchromatin and regulates gene expression. We used microarrays to analyse the changes in gene expression...
ORGANISM(S): Drosophila melanogaster 
2015-05-01 | E-GEOD-49103 | biostudies-arrayexpress
TranscriptomicsGene expression data for worker honey bees experimentally exposed to a dual infection with Deformed wing virus and Nosema ceranae.
Bees from 3 unrelated colonies were injected with 1ul PBS extract containing 10^9 genome equivalent of Deformed wIng virus (DWV) and/or fed 10µl sucrose solution containing 10^5 fresh Nosema ceranae spores. Control bees were injected and fed with an equivalent DWV- and Nosema-free extract respectiv...
ORGANISM(S): Apis mellifera 
2017-03-08 | E-MTAB-5508 | biostudies-arrayexpress
TranscriptomicsGene expression profile of experimentally Deformed wing virus (DWV)-infected honey bees: Naive control vs. DWV-infected pupae
Transcriptional profiling of honey bee pupae challenging a DWV infection by comparing the gene expression profiles of untreated honey bee pupae with DWV-infected pupae. Goal was to determine the gene expression profile of DWV-infected honey bee pupae.
ORGANISM(S): Apis mellifera 
2016-11-15 | E-MTAB-5070 | biostudies-arrayexpress
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