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TranscriptomicsEpigenetic environment of histone H3.3 on promoters revealed by integration of imaging, ChIP-chip, and MeDIP-chip data
Epigenetic environment of histone H3.3 on promoters revealed by integration of imaging and genome-scale chromatin and methyl-DNA immunoprecipitation information. Chromatin regions with different transcriptional outputs are distinguished by the deposition of histone variants. Histone H3.3 is incorpor...
ORGANISM(S): Homo sapiens 
2010-05-12 | E-GEOD-17053 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells
The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured hepatic stellate cells (HSCs), hepatocytes (HEPs) and liver sinusoidal endothelial cells (LSECs), by methylated DNA immunoprecipitation (MeDIP) and a...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-66796 | biostudies-arrayexpress
TranscriptomicsTranscriptome of human liver cells and culture-activated hepatic stellate cells
The molecular determinants of a healthy human liver cell phenotype remain largely uncharacterized. In addition, the gene expression changes associated with activation of primary human hepatic stellate cells, a key event during fibrogenesis, remain poorly characterized. Here, we provide the transript...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-68000 | biostudies-arrayexpress
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