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TranscriptomicsRNA-seq of zebrafish embryos exposed to different sublethal concentrations of tamoxifen for 96 hours against non-treated control groups
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio 
2023-05-10 | E-MTAB-12227 | biostudies-arrayexpress
TranscriptomicsRNA-seq of zebrafish embryos exposed to different sublethal concentrations of methyltestosterone for 96 hours against non-treated control groups
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio 
2023-05-10 | E-MTAB-12229 | biostudies-arrayexpress
TranscriptomicsRNA-seq of zebrafish embryos exposed to different sublethal concentrations of ethinylestradiol for 96 hours against non-treated control groups
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio 
2023-05-10 | E-MTAB-12221 | biostudies-arrayexpress
TranscriptomicsRNA-seq of zebrafish embryos exposed to different sublethal concentrations of flutamide for 96 hours against non-treated control groups
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio 
2023-05-10 | E-MTAB-12235 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of daphnia magna juveniles exposed to different sub-lethal concentrations of Imidacloprid in a modified acute immobilisation test below against untreated control groups
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in juvenile daphnids (daphnia magna) as aquatic vertebrate non-target model exposed to sub lethal concentrations of Imidacloprid. Imidacloprid is is a popular insecticide widely applied in agricultur...
ORGANISM(S): Daphnia magna 
2021-08-04 | E-MTAB-9830 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of daphnia magna juveniles exposed to different sub-lethal concentrations of Fipronil in a modified acute immobilisation test below against untreated control groups
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in juvenile daphnids (daphnia magna) as aquatic vertebrate non-target model exposed to sub lethal concentrations of Fipronil. Fipronil is a widely used insecticide applied for crop protection against...
ORGANISM(S): Daphnia magna 
2021-08-04 | E-MTAB-9829 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of Triiodothyronine (T3) below acute toxicity levels against untreated control groups
The aim of this sequencing experiment was to screen for ecotoxicogenomic fingerprints for endocrine disrupting chemicals affecting the thyroid system in zebrafish (Danio rerio) embryos as aquatic vertebrate model and alternative to animal testing. Triiodothyronine (T3, CAS: 6893-02-3) was tested as ...
ORGANISM(S): Danio rerio 
2020-09-30 | E-MTAB-9056 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of 6-Propyl-2-thiouracil (6-PTU) below acute toxicity levels against untreated control groups
Endocrine disruption can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. Ecotoxicogenomic screening was performed to identify molecular fingerprints for endocrine disrupting chemicals affecting the thyroid system in...
ORGANISM(S): Danio rerio 
2020-09-30 | E-MTAB-9054 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of zebrafish embryos (96hpf) exposed to different concentrations of Imidacloprid below acute toxicity levels against untreated control groups
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in zebrafish (Danio rerio) embryos as aquatic vertebrate non-target model exposed to sub lethal concentrations of the heavily used neonicotinoid insecticide Imidacloprid (CAS 138261-41-3). The Insect...
ORGANISM(S): Danio rerio 
2021-10-15 | E-MTAB-9859 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of zebrafish embryos (96hpf) exposed to different concentrations of Fipronil below acute toxicity levels against untreated control groups
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in zebrafish (Danio rerio) embryos as aquatic vertebrate non-target model exposed to sub lethal concentrations of the heavily used organophosphate insecticide Fipronil (CAS 2921-88-2). The Insecticid...
ORGANISM(S): Danio rerio 
2021-10-15 | E-MTAB-9854 | biostudies-arrayexpress
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