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TranscriptomicsA genome-wide and dose-dependent inhibition map of androgen receptor binding by small molecules reveals its regulatory program upon antagonism
The androgen receptor plays a critical role throughout the progression of prostate cancer and is an important drug target for this disease. While chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) is becoming an essential tool in studying transcription and chromatin...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-32892 | biostudies-arrayexpress
TranscriptomicsGenomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma [tumor]
Cancer is a genetic disease with frequent somatic alterations in DNA. Study of recurrent copy number aberrations (CNAs) in human cancers would enable the elucidation of disease mechanisms and the identification of key oncogenic drivers with causal roles in oncogenesis. We have comprehensively and sy...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38323 | biostudies-arrayexpress
TranscriptomicsPfizer Molecular Profile Data for Cell Lines
Baseline gene expression for cell lines growing in culture were measured by Affymetrix U133Plus2 arrays. Copy Number Variation for selected cell lines was also measured. Baseline gene expression for cell lines growing in culture were measured by Affymetrix U133Plus2 arrays. Three different sources...
ORGANISM(S): Homo sapiens 
2012-01-19 | E-GEOD-34211 | biostudies-arrayexpress
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