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TranscriptomicsFlagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii
Spirochetes are long, thin, motile, helical or flat wave bacteria that are unique among the prokaryotes by having flagella or axial filaments confined to an internal periplasmic space. These flagella are complex organelles that can play major roles in bacterial pathogenicity and are used as propelle...
ORGANISM(S): Borrelia hermsii 
2013-12-09 | E-GEOD-42863 | biostudies-arrayexpress
GenomicsBorrelia
Genome analysis of Hard tick borne relapsing fever Borrelia
PRJDB10961 | ENA
TranscriptomicsTranscription profiling of human umbilical vein endothelial cells treated with Interferon-gamma (IFN-g), Borrelia burgdorferi or both IFN-g and Borrelia or untreated to investigate immune responses to Lyme disease
Borrelia burgdorferi, the agent of Lyme disease, promotes pro-inflammatory changes in endothelium that lead to the recruitment of leukocytes. The host immune response to infection results in increased levels of IFN-gamma in the serum and lesions of Lyme disease patients that correlate with greater s...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6092 | biostudies-arrayexpress
ProteomicsProteomic Analysis of Lyme Disease: Global Protein Comparison of Three Strains of Borrelia Burgdorferi
We report the proteomic analysis of the archetype B. burgdorferi B31 strain and two other strains (ND40, and JD-1) having different Borrelia pathotypes using strong cation exchange fractionation of proteolytic peptides followed by high-resolution, reversed phase capillary liquid chromatography coupl...
ORGANISM(S): Borreliella Burgdorferi (ncbitaxon:139) 
2020-05-29 | MSV000085503 | MassIVE
TranscriptomicsTranscriptional responses of normal human dermal fibroblasts (NHDF) induced by Borrelia burgdorferi sensu stricto
The aim of the study was to compare the global transcriptional responses elicited in NHDF cells by three different strains of Borrelia burgdorferi ss (the agent of Lyme borreliosis), representative of different stages in the life cycle of Borrelia: one reference strain isolated from a tick (strain ...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-31740 | biostudies-arrayexpress
GenomicsTick-Borne Relapsing Fever caused by Borrelia persica in a Traveler returning from Central Asia
Tick-Borne Relapsing Fever caused by Borrelia persica in a Traveler returning from Central Asia
PRJEB35490 | ENA
TranscriptomicsBorrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi
Our study is the first to demonstrate BadR as a repressor of rpoS and thus facilitates spirocheteM-bM-^@M-^Ys transition back into ticks. BadR binds upstream and represses rpoS in unfed ticks. GLcNA-6P, an abundant nutrient of blood and released by subsequent remodeling of the tick peritrophic memb...
ORGANISM(S): Borrelia burgdorferi B31 
2013-02-22 | E-GEOD-38827 | biostudies-arrayexpress
GenomicsBorrelia recurrentis A1 strain:A1
Causes louse-borne relapsing fever
PRJNA18233 | ENA
GenomicsBorrelia hermsii DAH
Causes tick-borne relapsing fever
PRJNA29637 | ENA
ProteomicsIdentification of the effect of a CRISPR interference knockdown of Borrelia burgdorferi strain B31 BB0838, a outer membrane lipoprotein flippase candidate, on surface lipoprotein secretion using Multidimensional Protein Identification Technology.
To identify the effect of a CRISPR interference knockdown of Borrelia burgdorferi strain B31 BB0838, a outer membrane lipoprotein flippase candidate, on surface lipoprotein secretion using Multidimensional Protein Identification Technology.
ORGANISM(S): Borrelia Burgdorferi B31 (ncbitaxon:224326) 
2022-07-27 | MSV000089990 | MassIVE
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