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In this study, by using two classical macrophage cell models, RAW264.7 cell line from mouse and THP-1 cell line from human, combined with the applications of two classical stimulation methods for inducing classical activated (M1) and alternatively activated macrophages (M2) from the monocytes of bot...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-06-18 | PXD019800 | Pride
We profile the binding of Steroid Receptor Co-activator (SRC1) in LY2 cells, a tamoxifen-resistant cell line, in the presence and absence of tamoxifen using ChIP-sequencing technology. The development of breast cancer resistance to endocrine therapy results from an increase in cellular plasticity le...
ORGANISM(S): Homo sapiens 
This work comprehensively compared 50 mM of ammonium acetate (pH 6), Tris-HCl (pH 8), ABC and TEAB as in-solution trypsin digestion buffers. Both iTRAQ quantification and label-free results indicate that ammonium acetate (pH 6) is more suitable than other buffers for studying endogenous deamidation ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-28 | PXD001650 | Pride
The development of breast cancer resistance to endocrine therapy results from an increase in cellular plasticity leading to the development of a steroid independent tumour. The p160 steroid coactivator protein SRC-1, through interactions with developmental proteins and other non-steroidal transcrip...
ORGANISM(S): Homo sapiens 
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