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TranscriptomicsscRNAseq libraries of pooled kidney samples from wild type (ZF1) versus CRISPR-targeted renin knockout (ZF2) zebrafish
Libraries were made to compare the transcriptome of renin lineage cells (RLCs) from wild-type versus ren knockout zebrafish kidneys. RLCs were FAC sorted from pooled kidneys of ren+/+ or ren-/- zebrafish, which carried ren:RFP and acta2:EGFP reporter genes, allowing the isolation of renin-expressin...
ORGANISM(S): Danio rerio 
2022-06-10 | E-MTAB-11079 | biostudies-arrayexpress
GenomicsMouse spleen: Histone modification patterns in spleens from wild type and leukemic mice
ChIP-Seq for H3K4me3 and H3K27me3 in wild type spleens and spleens from mice having deletion of RBP-J in cells of the renin lineage, which results in B-cell leukemia. Examination of 2 different histone modifications in wild type and mutant spleens.
ORGANISM(S): Mus musculus 
2014-02-17 | E-GEOD-46566 | biostudies-arrayexpress
TranscriptomicsGenome-wide microRNA expression induced by TNF
We sequenced microRNAs from bone marrow derived macrophages derived from the control (WT) and RBP-J conditional knockout mice (RBP-J KO; Rbpjf/f; LysM Cre). Examination of differential microRNA expression levels induced by TNF as well as regulated by RBP-J in bone marrow derived macrophages.
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-72966 | biostudies-arrayexpress
TranscriptomicsExpression data from follicle associated epithelium (FAE) of small intestine in wild type C57BL/6 mice or mice depleted with RBP-J (by VillinCre-Rbpjflox/flox)
To investigate the role of RBP-J in regulating epithelial cell differention in small intestine, we isolated FAE from mice depleted with RBP-J FAE were isolated from mice described above. Total RNA were extracted from the tissue by QIAGEN Rneasy mini kit.
ORGANISM(S): Mus musculus 
2014-09-04 | E-GEOD-61058 | biostudies-arrayexpress
UnknownThe tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication.
Not available
S-EPMC8237968 | biostudies-literature
UnknownThe histone methyltransferase Setd2 is indispensable for V(D)J recombination.
Not available
S-EPMC6659703 | biostudies-literature
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
TranscriptomicsV(D)J BCR single cell sequencing of mucosal pinch biopsies from patients with ulcerative colitis and primary sclerosing cholangitis concomitant with colitis
Mucosal pinch biopsies from ascending, transverse, descending colon and rectum were obtained from ulcerative colitis (UC) and primary sclerosing cholangitis concomitant with colitis (PSC-UC) patients during routine endoscopies and subjected to 5' single-cell RNA sequencing with V(D)J BCR analysis
ORGANISM(S): Homo sapiens 
2026-06-17 | E-MTAB-14901 | biostudies-arrayexpress
UnknownIn situ orderly self-assembly strategy affording NIR-II-J-aggregates for in vivo imaging and surgical navigation.
Not available
S-EPMC10070396 | biostudies-literature
UnknownDevelopment of a loop-mediated isothermal amplification assay for rapid detection of subgroup J avian leukosis virus.
Not available
S-EPMC2884476 | biostudies-literature
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