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MetabolomicsFaecalibaculum rodentium as a key player in combating maternal obesity-induced labor disorders

The global rise in maternal obesity increases the risk of adverse maternal and neonatal outcomes. This study demonstrates that both long- (12 weeks) and short-term (gestational) exposure to a high-fat diet (HFD) induces uterine labor disorders, elevates stillbirth rates, and alters gut microbiota...

2025-08-22 | MTBLS12877 | MetaboLights
TranscriptomicsTranscriptional Profiling is Superior to Procalcitonin to Discriminate Bacterial vs. Viral Lower Respiratory Tract Infections in Hospitalized Adults
Background: Distinguishing between bacterial and viral lower respiratory tract infections (LRTI) in hospitalized patients remains challenging. Transcriptional profiling is a promising tool for improving diagnosis in LRTI. Methods: We performed whole blood transcriptional analysis in a cohort of ...
ORGANISM(S): Homo sapiens 
2015-09-14 | E-GEOD-60244 | biostudies-arrayexpress
TranscriptomicsCombined Chronic Toxicity and Carcinogenicity of Aerosol from a Heated Tobacco Product (microRNA data).
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus 
2020-08-17 | E-MTAB-8541 | biostudies-arrayexpress
TranscriptomicsCombined Chronic Toxicity and Carcinogenicity of Aerosol from a Heated Tobacco Product (mRNA data)
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus 
2020-08-17 | E-MTAB-8540 | biostudies-arrayexpress
ProteomicsUrine proteome analysis in the differential diagnostics of respiratory tract pathology in newbornes under intensive care
To investigate the possibility of using modern mass spectrometric methods for forecasting, early diagnosis of the causes of respiratory diseases, as well as monitoring the effectiveness of treatment of newborns with very low and extremely low birth weight infants. Results: Based on the analysis of l...
ORGANISM(S): Homo sapiens (Human) 
2016-06-21 | PXD001773 | Pride
Preterm newborn Very low birth weight Urine Respiratory tract disorders Neonatal intensive care Proteome 
TranscriptomicsVitamin A-deficient mice experience increased viral antigens and enhanced cytokine/chemokine production in nasal tissues following respiratory virus infection despite the presence of FoxP3+ T cells
Vitamin A deficiencies and insufficiencies affect hundreds of millions of people in both developing and developed countries. These individuals experience higher rates of mortality and increased morbidity during enteric and respiratory infections compared to those who are vitamin A sufficient. Previo...
ORGANISM(S): Mus musculus 
2016-02-11 | E-GEOD-65805 | biostudies-arrayexpress
TranscriptomicsBronchial Airway Gene Expression in Smokers with Lung or Head and Neck Cancer
Cigarette smoking is the major cause of cancers of the respiratory tract, including non-small cell lung cancer (NSCLC) and head and neck cancer (HNC). In order to better understand carcinogenesis of the lung and upper airways, we have compared the gene expression profiles of tumour-distant, histolog...
ORGANISM(S): Homo sapiens 
2014-05-24 | E-MTAB-1690 | biostudies-arrayexpress
TranscriptomicsNasal epithelium gene expression profiling in child respiratory allergic disease
Background: In asthma, airway epithelium remodeling can already be detected during childhood, and epithelial cells are more susceptible to virus and oxidative stress. Their exact role in natural history and severity of children allergic respiratory disease remains however surprisingly unexplored. A...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-19187 | biostudies-arrayexpress
UnknownEvaluation of Drug Interactions in Hospitalized Patients with Respiratory Disorders in Greece.
Not available
S-EPMC9952796 | biostudies-literature
TranscriptomicsProfiling of bacterial respiratory infection, viral respiratory infection, and non-infectious illness
A pressing clinical challenge is identifying the etiologic basis of acute respiratory illness. Without reliable diagnostics, the uncertainty associated with this clinical entity leads to a significant, inappropriate use of antibacterials. Use of host peripheral blood gene expression data to classify...
ORGANISM(S): Homo sapiens 
2016-01-20 | E-GEOD-63990 | biostudies-arrayexpress
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