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ProteomicsLC-MS/MS analysis of pancreatic cancer plasma
Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the de-velopment of effective diagnostic, prognostic and predictive biomarkers for disease manage-ment. Aberrantly fucosylated proteins in PC are considered a valuable resource of clinically useful biomarkers. T...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD025150 | Pride
Itraq-based quantitative proteome Pancreatic cancer Aal Fucosylated serpina1 Plasma Glycobiomarker Reverse lectin-based elisa 
UnknownAnalysis of glycan variation on glycoproteins from serum by the reverse lectin-based ELISA assay.
Not available
S-EPMC3993964 | biostudies-literature
UnknownIdentification of Fucosylated SERPINA1 as a Novel Plasma Marker for Pancreatic Cancer Using Lectin Affinity Capture Coupled with iTRAQ-Based Quantitative Glycoproteomics.
Not available
S-EPMC8200073 | biostudies-literature
UnknownEfficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicides.
Not available
S-EPMC3632893 | biostudies-literature
ProteomicsN-linked glycoproteins from exosome-depleted excretory-secretory products of fourth-stage larval Angiostrongylus cantonensis promotes alternative activation of macrophages through metabolic reprogramming by the PI3K-Akt pathway
Angiostrongylus cantonensis (AC), which parasitizes in the brain of the non-permissive host, such as mouse and human, is an etiologic agent of eosinophilic meningitis. Excretory-secretory (ES) products play an important role in the interaction between parasites and hosts’ immune responses. Inflammat...
ORGANISM(S): Angiostrongylus cantonensis 
2021-07-28 | PXD025218 | Pride
Exosome-depleted excretory-secretory products N-linked glycoproteins Mechanism Angiostrongylus cantonensis Macrophage polarization 
ProteomicsProteomics of active poly articular Juvenile idiopathic arthritis compared to healthy controls by combined mass spectrometry and bioinformatics approach
Juvenile idiopathic arthritis (JIA) refers to any type of chronic arthritis that develops before the age of sixteen, lasts longer than six weeks, and has an unknown etiology. The existing diagnostic techniques for JIA are conventional and occasionally ineffective at distinguishing JIA from other ped...
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD058863 | Pride
Human Juvenile idiopathic arthritis Proteomics 
ProteomicsHuman synovial fluid proteomics reveals potential early-diagnostic biomarkers for ankylosing spondylitis
[Background] Ankylosing spondylitis (AS), affecting 0.5% of the population, is a chronic inflammatory rheumatic disease affecting the axial skeleton and peripheral joints. The etiology of this disease is still poorly understood, but it may be involved with the interaction of genetic and environmen...
ORGANISM(S): Homo sapiens (Human) 
2021-07-15 | PXD016620 | Pride
Synovial fluid Proteomics Biomarker Ankylosing spondylitis 
TranscriptomicsDivergent influence of microRNA-21 deletion on murine colitis phenotypes [mRNA]
Background: MicroRNAs (miRNAs) acting as negative regulators of gene expression are differentially expressed in intestinal tissues of patients with inflammatory bowel disease (IBD). Assessing the functional role of miRNAs in murine models of colitis facilitates elucidating the role of specific miRN...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-59648 | biostudies-arrayexpress
TranscriptomicsDivergent influence of microRNA-21 deletion on murine colitis phenotypes [TNBS]
Background: MicroRNAs (miRNAs) acting as negative regulators of gene expression are differentially expressed in intestinal tissues of patients with inflammatory bowel disease (IBD). Assessing the functional role of miRNAs in murine models of colitis facilitates elucidating the role of specific miRN...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-59650 | biostudies-arrayexpress
TranscriptomicsDivergent influence of microRNA-21 deletion on murine colitis phenotypes [DSS]
Background: MicroRNAs (miRNAs) acting as negative regulators of gene expression are differentially expressed in intestinal tissues of patients with inflammatory bowel disease (IBD). Assessing the functional role of miRNAs in murine models of colitis facilitates elucidating the role of specific miRN...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-59649 | biostudies-arrayexpress
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