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TranscriptomicsDNA methylation profiling of glioblastoma cancer stem cells
Glioblastoma (GBM) is thought to be driven by a sub-population of cancer stem cells (CSCs) that self-renew and recapitulate tumor heterogeneity, yet remain poorly understood. Here we present a comparative epigenomic analysis of GBM CSCs that reveals widespread activation of genes normally held in ch...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-46015 | biostudies-arrayexpress
GenomicsEpigenomic profiling of glioblastoma stem cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-46016 | biostudies-arrayexpress
TranscriptomicsExpression profiling of glioblastoma cancer stem cells
Glioblastoma (GBM) is thought to be driven by a sub-population of cancer stem cells (CSCs) that self-renew and recapitulate tumor heterogeneity, yet remain poorly understood. Here we present a comparative epigenomic analysis of GBM CSCs that reveals widespread activation of genes normally held in ch...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-45899 | biostudies-arrayexpress
GenomicsHistone modification and TF ChIP-Seq for glioblastoma cell lines and neural stem cells
Glioblastoma (GBM) is thought to be driven by a sub-population of cancer stem cells (CSCs) that self-renew and recapitulate tumor heterogeneity, yet remain poorly understood. Here we present a comparative epigenomic analysis of GBM CSCs that reveals widespread activation of genes normally held in ch...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-46014 | biostudies-arrayexpress
UnknownReconstructing and reprogramming the tumor propagating potential of glioblastoma stem-like cells: RNA-seq
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-54791 | biostudies-other
GenomicsMapping polycomb complexes in human and mouse embryonic stem cells
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2000 genes. To gain insight into the structure and function of bivalent domains, we m...
ORGANISM(S): Mus musculus 
2008-11-01 | E-GEOD-13084 | biostudies-arrayexpress
TranscriptomicsReconstructing and reprogramming the tumor propagating potential of glioblastoma stem-like cells: RNA-seq
Developmental fate decisions are dictated by master transcription factors (TFs) that interact with cis-regulatory elements to direct transcriptional programs. Certain malignant tumors may also depend on a cellular hierarchy reminiscent of normal development but superimposed on underlying genetic abe...
ORGANISM(S): Homo sapiens 
2014-04-14 | E-GEOD-54791 | biostudies-arrayexpress
GenomicsReconstructing and reprogramming the tumor propagating potential of glioblastoma stem-like cells: ChIP-seq
Developmental fate decisions are dictated by master transcription factors (TFs) that interact with cis-regulatory elements to direct transcriptional programs. Certain malignant tumors may also depend on a cellular hierarchy reminiscent of normal development but superimposed on underlying genetic abe...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-54047 | biostudies-arrayexpress
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