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TranscriptomicsGene expression in soleus muscle of mouse inbred strains LG/J and SM/J
Variability in muscle mass significantly impacts energy expenditure, influencing preponderance to obesity and recently it has been reported that there is a positive association between muscle mass and longevity in older adults. Muscle fibre cross-sectional area (CSA) and proportion of different fibr...
ORGANISM(S): Mus musculus 
2017-01-23 | E-MTAB-5290 | biostudies-arrayexpress
TranscriptomicsIntegrated host and viral transcriptome analyses reveal pathology and inflammatory response mechanisms to ALV-J injection in SPF chicken
Avian leukosis virus (ALV) causes substantial economic losses from mortality and decreased performance in poultry industry. To characterize the response to ALV challenge, we developed a novel methodology that combines four datasets: mRNA expression and their associated regulatory factors of miRNA an...
ORGANISM(S): Gallus gallus 
2017-10-04 | E-MTAB-5135 | biostudies-arrayexpress
TranscriptomicsRNAseq of A/J mice spiral ganglion derived neurospheres vs differentiated auditory neurons
Sphere-forming progenitor cells can be isolated from the fetal and adult mammalian inner ear and give rise to inner ear specific cell types in vitro. Here, we provide phenotypical and functional characterization of a new pool of auditory progenitors as sustainable source for sphere-derived auditory ...
ORGANISM(S): Mus musculus 
2020-08-29 | E-MTAB-9441 | biostudies-arrayexpress
TranscriptomicsExpression of brain gene at P4 and P10 post-coïtus in the rat, after protein restriction of the mother regimen during gestation
Total brain was collected from newborn rats that were growth-restricted obtained by feeding the females a low-protein diet during pregnancy. The model was extensively described in Buffat et al, J. Pathology 2007, and Zana-Taieb et al, J. Pathology, 2015.
ORGANISM(S): Rattus norvegicus 
2016-10-14 | E-MTAB-4646 | biostudies-arrayexpress
TranscriptomicsCombined Chronic Toxicity and Carcinogenicity of Aerosol from a Heated Tobacco Product (microRNA data).
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus 
2020-08-17 | E-MTAB-8541 | biostudies-arrayexpress
TranscriptomicsExpression quantitative trait loci (eQTL) analysis of mouse lung tumors
To detect genetic variations affecting gene expression in mouse lung tumor tissue, we carried out a genetic linkage study on the transcriptome of lung tumors induced by urethane in an (A/J x C57BL/6)F4 intercross population, whose individual lung tumor multiplicity (Nlung) is linked to the genotype ...
ORGANISM(S): Mus musculus 
2016-03-14 | E-GEOD-71232 | biostudies-arrayexpress
TranscriptomicsCombined Chronic Toxicity and Carcinogenicity of Aerosol from a Heated Tobacco Product (mRNA data)
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus 
2020-08-17 | E-MTAB-8540 | biostudies-arrayexpress
UnknownSerotonergic psychedelics temporarily modify information transfer in humans.
Not available
S-EPMC4571623 | biostudies-literature
TranscriptomicsTranscriptomics and physiological analyses reveal coordinated alteration of metabolic pathways in Jatropha curcas drought tolerance
Jatropha curcas, a multipurpose plant attracting much attention due to its high oil content and quality for biofuel, is recognized as a drought tolerant species. However, this drought tolerance is still poorly characterized. This study aims to contribute to uncover the molecular background of this t...
ORGANISM(S): Jatropha curcas 
2015-12-09 | E-GEOD-61109 | biostudies-arrayexpress
TranscriptomicsProfiling neuroblastoma SH-SY5Y with Paraquat treatment
Human SH-SY5Y neuroblastoma cells treated with paraquat, a neurotoxic herbicide which both catalyzes the formation of reactive oxygen species (ROS) and induces mitochondrial damage in animal models was profiled using Affimetrix Exon 1.0 ST GeneChips® Human SH-SY5Y neuroblastoma cells was compared w...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-21305 | biostudies-arrayexpress
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