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MetabolomicsPKA regulates stress granule maturation to allow timely recovery after prolonged starvation
Cells have evolved multiple strategies to survive environmental stress conditions. This includes the formation of membrane-less cytoplasmic ribonucleoprotein structures called stress granules that sequester and protect mRNAs encoding many housekeeping genes. Stress granules are not static biomolecul...
2026-06-16 | MTBLS13923 | MetaboLights
UnknownDirect observation of translational activation by a ribonucleoprotein granule.
Not available
S-EPMC11321996 | biostudies-literature
GenomicsDEAD-Box Helicase 3 Modulates the Non-Coding RNA Pool in Ribonucleoprotein Condensates During Stress Granule Formation
DEAD-Box Helicase 3 Modulates the Non-Coding RNA Pool in Ribonucleoprotein Condensates During Stress Granule Formation
PRJNA1294212 | ENA
ProteomicsFAM69C functions as a kinase for eIF2α and promotes stress granule assembly
Stress granules are dynamic cytoplasmic ribonucleoprotein granules that assemble in response to cellular stress. Aberrant formation of stress granules has been linked to neurodegenerative diseases. However, the molecular mechanisms underlying the initiation of stress granules remain elusive. Here we...
ORGANISM(S): Homo sapiens (Human) 
2023-04-21 | PXD037697 | Pride
Eif2α  fam69c  inflammasome  stress response  stress granule. 
ProteomicsContext-dependent and disease-specific diversity in stress granules formed from preexisting protein interactions
Affinity-capture proteomics studies using endogenously tagged G3BP1 with APEX2 to capture the stress granule proteome at steady state and upon stress induction. This was done in 293T cells as well as induced pluripotent stem cells differentiated into neuronal progenitor cells.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081554 | MassIVE
TranscriptomicsMutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma
This SuperSeries is composed of the following subset Series: GSE25774: Genome-wide analysis of Tdrd7 knockdown in lens epithelial-derived cell line 21EM15 GSE25775: Genome-wide analysis of 4-day old (P4) Tdrd7 null mouse lens GSE25776: Genome-wide analysis of 1 month old (P30) Tdrd7 null mouse lens ...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-25812 | biostudies-arrayexpress
ProteomicsIntracellular Energy Controls Dynamics of Stress-induced Ribonucleoprotein Granules Implicated in ALS/FTD
Energy metabolism and membraneless organelles have been implicated in human diseases including neurodegeneration. How energy deficiency regulates ribonucleoprotein particles such as stress granules (SGs) is still unclear. Here we identified a unique type of granules formed under energy deficiency an...
ORGANISM(S): Homo sapiens (Human) 
2022-10-15 | PXD035747 | Pride
Stress granule  energy metabolism  als/ftd  protein homeostasis 
TranscriptomicsDEAD-Box Helicase 3 Modulates the Non-Coding RNA Pool in Ribonucleoprotein Condensates During Stress Granule Formation
Stress granule formation is a type of liquid–liquid phase separation in the cytoplasm, leading to RNA–protein condensates that are associated with various cellular stress responses and implicated in numerous pathologies, including cancer, neurodegeneration, inflammation, and cellular senescence. One...
ORGANISM(S): Homo sapiens 
2025-09-03 | GSE303136 | GEO
UnknownDEAD-Box Helicase 3 Modulates the Non-Coding RNA Pool in Ribonucleoprotein Condensates During Stress Granule Formation.
Not available
S-EPMC12388690 | biostudies-literature
UnknownSCD6 induces ribonucleoprotein granule formation in trypanosomes in a translation-independent manner, regulated by its Lsm and RGG domains.
Not available
S-EPMC3694794 | biostudies-literature
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