Synonymous mutations do not change the sequence of the polypeptide but they may still influence fitness. We investigated in Salmonella enterica how four synonymous mutations in the rpsT gene (encoding ribosomal protein S20) reduce fitness (i.e. growth rate) and the mechanisms by which this cost can...
ORGANISM(S): Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)