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UnknownRole and dynamics of the ribosomal protein P0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae.
Not available
S-EPMC2794172 | biostudies-literature
UnknownRecombinant expression and biophysical characterization of Mrt4 protein that involved in mRNA turnover and ribosome assembly from Saccharomyces cerevisiae.
Not available
S-EPMC9161856 | biostudies-literature
ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD068797 | Pride
Invasive fungal infections Protein-rna interaction covalent inhibitors Fumaramidmycin derivatives Ribosome assembly factor mrt4 Antifungal target identification 
TranscriptomicsRiBi project double mutants
The RiBi project investigated the role of chromatin factor Spt6 in ribosome biogenesis. In this experiment we performed transcription profiling of Saccharomyces cerevisiae single and double deletion mutants involved in ribosome assembly. The single mutants examined in this experiment were: arx1-dele...
ORGANISM(S): Saccharomyces cerevisiae 
2017-07-06 | E-MTAB-4574 | biostudies-arrayexpress
ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy-qualitative proteomic
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD073550 | Pride
Ribosome assembly factor Azole-resistant fungi Protein-rna interaction Fumaramidmycin-based derivatives Target identification 
UnknownCarboxy terminal modifications of the P0 protein reveal alternative mechanisms of nuclear ribosomal stalk assembly.
Not available
S-EPMC3794597 | biostudies-literature
UnknownThe composition and turnover of the Arabidopsis thaliana 80S cytosolic ribosome.
Not available
S-EPMC7452503 | biostudies-literature
UnknownPollen Number and Ribosome Gene Expression Altered in a Genome-Editing Mutant of REDUCED POLLEN NUMBER1 Gene.
Not available
S-EPMC8787260 | biostudies-literature
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