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TranscriptomicsExpression of sense and antisense transcripts at the ribosomal locus
Epigenetic methyl-CpG silencing of the ribosomal RNA (rRNA) genes is thought to down-regulate rRNA synthesis in mammals. In contrast, we now show that CpG methylation in fact positively influences rRNA synthesis and processing. Human HCT116 cells, inactivated for DNMT1 and DNMT3b or treated with aza...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-17042 | biostudies-arrayexpress
UnknownNucleolar stress enhances lytic reactivation of the Kaposi's sarcoma-associated herpesvirus.
Not available
S-EPMC5862618 | biostudies-literature
GenomicsRibosome profiling and RNA-seq of Rat whole brain
Ribosome profiling and RNA-seq of Rat whole brain
PRJNA725707 | ENA
UnknownA trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
Not available
S-EPMC10135430 | biostudies-literature
UnknownTERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis.
Not available
S-EPMC10468137 | biostudies-literature
UnknownMechanistic Insight into the Reactivation of BCAII Enzyme from Denatured and Molten Globule States by Eukaryotic Ribosomes and Domain V rRNAs.
Not available
S-EPMC4839638 | biostudies-literature
TranscriptomicsRibosome profiling and RNA-seq of Rat whole brain
Local translation in neurons is mediated in part by the reactivation of stalled polysomes. However, the mechanism for stalling of the polysomes is not understood. Stalled polysomes may be enriched in neuronal RNA granules defined by dense collections of compacted ribosomes found in the pellet of suc...
ORGANISM(S): Rattus norvegicus 
2023-04-01 | GSE173464 | GEO
UnknownAmino acid deprivation triggers a novel GCN2-independent response leading to the transcriptional reactivation of non-native DNA sequences.
Not available
S-EPMC6051655 | biostudies-literature
ProteomicsRiboproteome remodelling during quiescence exit in Saccharomyces cerevisiae
Characterization of the riboproteome composition in quiescent cells and post-translational reactivation. To characterize ribosome heterogeneity during the exit from quiescence, the protein composition of ribosomal particles from stationary phase and nutrient-stimulated cells was assessed. A label-fr...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-12-20 | PXD047386 | Pride
Mass spectrometry Ribosome Saccharomyces cerevisiae 
TranscriptomicsArabidopsis SE coordinates histone methyltransferases ATXR5/6 and RNA processing factor RDR6 to regulate transposon expression [RNA-Seq]
We performed Illumina sequencing of ribosome depletion RNA libraries prepared from 10-day-old seedlings in Arabidopsis. SE is required for transposon reactivation in atxr5 atxr6 mutant.
ORGANISM(S): Arabidopsis thaliana 
2018-06-26 | GSE111812 | GEO
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