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TranscriptomicsExpression data from human glioma cancer stem cell (CSC) specimens following knockdown of GREM1
CSCs differentially secrete the BMP antagonist Gremlin1 compared to non-stem glioma populations. Knockdown of Gremlin1 decreases CSC proliferation and tumorigenicity, establishing Gremlin1 as an essential effector for CSC maintenance. We used a microarray to determine the gene expression programs t...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-52846 | biostudies-arrayexpress
UnknownThe proline-rich domain promotes Tau liquid-liquid phase separation in cells.
Not available
S-EPMC7594490 | biostudies-literature
TranscriptomicsTranscriptome profiling of leaves in two genotypes of perennial ryegrass during cold acclimation
The changes in the transcriptome of leaves between 0, 9, 13 and 17 days of cold acclimation were analyzed using RNA-Seq in Veyo and Falster genotypes of perennial ryegrass.
ORGANISM(S): Lolium perenne 
2016-04-20 | E-MTAB-2779 | biostudies-arrayexpress
MetabolomicsSalmonella Modulates Metabolism during Growth under Conditions that Induce Expression of Virulence Genes
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative pathogen that uses complex mechanisms to invade and proliferate within mammalian host cells. To investigate possible contributions of metabolic processes to virulence in S. Typhimurium grown under conditions known to induce ex...
2013-05-02 | MTBLS35 | MetaboLights
UnknownThe impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial.
Not available
S-EPMC7948850 | biostudies-literature
UnknownMicronutrient-rich dietary intake is associated with a reduction in the effects of particulate matter on blood pressure among electronic waste recyclers at Agbogbloshie, Ghana.
Not available
S-EPMC7339459 | biostudies-literature
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
UnknownEnigmatic H<sub>2</sub>- and CH<sub>4</sub>-rich hydrothermal plumes at the ultramafic-hosted Lucky B site, 81°N on Lena Trough, Arctic Ocean.
Not available
S-EPMC12521595 | biostudies-literature
ProteomicsCancer Stem Cells Induce Proline Synthesis through FAM3C-Mediated SPIN1 Stabilization to Attenuate ROS Stress
Tumors reprogram amino acid metabolism to dysregulate cellular growth through multiple mechanisms. Here, we find that glioblastoma (GBM) stem cells (GSCs) contain increased proline levels relative to differentiated GBM cells (DGCs) through increased proline synthesis. We identified FAM3C (FAM3 Metab...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD068325 | Pride
Glioma stem cell Glioblastoma Proline Ros 
UnknownMyosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.
Not available
S-EPMC5393228 | biostudies-literature
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