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TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant upl3-4 Arabidopsis thaliana plants.
Activation of plant immunity is associated with dramatic transcriptome reprogramming to prioritise immune responses over normal cellular functions. Changes in gene expression are coordinated by the immune hormone salicylic acid (SA). Here we investigated the involvement of the HECT-type ligase Ubiqu...
ORGANISM(S): Arabidopsis thaliana 
2018-11-09 | E-MTAB-7374 | biostudies-arrayexpress
TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant ube4 Arabidopsis thaliana plants
Activation of plant immunity is associated with dramatic transcriptome reprogramming to prioritise immune responses over normal cellular functions. Changes in gene expression are coordinated by the immune hormone salicylic acid (SA). Here we investigated the involvement of the E4 ubiquitin ligase UB...
ORGANISM(S): Arabidopsis thaliana 
2019-03-20 | E-MTAB-7369 | biostudies-arrayexpress
ProteomicsEngineered allostery in a light-regulated version of TurboID for precise spatiotemporal control of proximity labeling in living cells
Lee SY, Chea JS, Zhao BX, Xu C, Udeshi ND, Roh H, Kim C, Cho K, Carr SA, Ting A. 2022 The incorporation of light-responsive domains into engineered proteins has produced optogenetic tools with the ability to regulate protein localization, interactions, and function with light. We introduced this mod...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-09 | MSV000090683 | MassIVE
TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant upl1, upl5, and npr1-1 Arabidopsis thaliana plants
The plant immune hormone salicylic acid (SA) modulates transcriptional reprogramming via controlling the master transcriptional coactivator, NPR1. Here we examined the role of HECT-type ubiquitin ligases, UPL1 and UPL5, in SA/NPR1-dependent transcriptional control. We showed that UPL1 and UPL5 are e...
ORGANISM(S): Arabidopsis thaliana 
2021-10-05 | E-MTAB-10963 | biostudies-arrayexpress
TranscriptomicsAzelaic acid mediated priming of salicylic acid signalling in Arabidopsis thaliana
Azelaic acid (AzA) is a candidate systemic resistance inducing phloem mobile signal in Aarabidopsis thaliana, but whether it interacts with immune signalling and how is not known. Here we investigated the crosstalk between phloem signal AzA and immune inducing phytohormone salicylic acid (SA). We sh...
ORGANISM(S): Arabidopsis thaliana 
2024-12-25 | E-MTAB-14632 | biostudies-arrayexpress
TranscriptomicsN-hydroxy-pipecolic acid mediated priming of salicylic acid signalling in Arabidopsis thaliana
N-hydroxy-pipecolic acid (NHP) primes Aarabidopsis thaliana to confer faster and stronger activation of immune responses, but how NHP interacts with other immune-inducing phytohormones is unknown. Here we investigated the crosstalk between priming phytohormone NHP and immune inducing phytohormone sa...
ORGANISM(S): Arabidopsis thaliana 
2024-12-25 | E-MTAB-14631 | biostudies-arrayexpress
ProteomicsBombardier mediates delivery of short-form Bomanins in the Drosophila Toll response
Toll mediates a robust and effective innate immune response across vertebrates and invertebrates. In Drosophila melanogaster, activation of Toll by systemic infection drives the accumulation of a rich repertoire of immune effectors in hemolymph, including the recently characterized Bomanins as well ...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2019-10-25 | MSV000084509 | MassIVE
TranscriptomicsN-hydroxy-pipecolic acid mediated priming of salicylic acid signalling in Arabidopsis thaliana wrky38/wrky62 double mutants
N-hydroxy-pipecolic acid (NHP) primes Aarabidopsis thaliana to confer faster and stronger activation of immune responses, in part by priming salicylic acid (SA) signalling. Here we investigated the potential regulators of NHP-SA crosstalk in priming. We show that in wrky38/wrky62 double mutants, SA ...
ORGANISM(S): Arabidopsis thaliana 
2025-03-01 | E-MTAB-14847 | biostudies-arrayexpress
ProteomicsSTAG2 Loss Rewires Oncogenic and Developmental Programs to Promote Metastasis in Ewing Sarcoma
Adane B, Alexe G, Seong BKA, Lu D, Hwang E, Hnisz D, Lareau CA, Ross L, Lin S, Dela Cruz FS, Richardson M, Weintraub AS, Wang S, Balboni-Iniguez A, Dharia NV, Conway AS, Robichaud AL, Tanenbaum B, Krill-Burger JM, Vazquez F, Schenone M, Berman JN, Kung A, Carr SA, Aryee MJ, Young RA, Crompton BD, St...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082954 | MassIVE
GenomicsARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
We have sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component of the SWI–SNF chromati...
EGAS00000000075 | EGA
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