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We have used oligoarray comparative genomic hybridization (aCGH) to identify novel suppressors generated in a UV-TMP based suppressor screen. This approach is suitable for detecting single gene mutations as well as copy number variations. Keywords: C.elegans Suppressor screen array CGH [1] 2 test s...
ORGANISM(S): Caenorhabditis elegans 
Effect of knock down of LASP-1 on luminal breast cancer cells (MCF7)
Effect of knock down of LASP-1 on basal-like breast cancer cells (MDA-MB-231)
To determine how mutation of BRAF affected the response to RAF265, we utilized a tumor orthotopic implant model of early passage melanoma tumors in nude mice from a series of 17 patients with advanced metastatic Tumor growth was compared between RAF265 treatment (40 mg/kg, QD) and diluent control gr...
ORGANISM(S): Homo sapiens 
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