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TranscriptomicsTranscription profiling of human TRAIL-resistant metastatic vs primary TRAIL-sensitive melanoma cells
T1 and G1 are the two melanoma cell lines, established from primary tumor (T1) and lymph node metastases (G1) of a 77 years old male patient. While G1 cells were resistant to TRAIL (TNF-related apoptosis-inducing ligand) mediated cell death, T1 cells exhibited a high dose- and time-dependent sensiti...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-247 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human Burkitts lymphoma samples
Additional chromosomal abnormalities are currently detected in Burkitt’s lymphoma. They play major roles in the progression of BL and in prognosis. The genes involved remain elusive. A whole-genome oligonucleotide array CGH analysis correlated with karyotype and FISH was performed in a set of 15 Bu...
ORGANISM(S): Homo sapiens 
2009-09-18 | E-TABM-703 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of a mother and daughter with a familial translocation t(2;6)(p25;p21) balanced in the mother and unbalanced in the daughter to determine breakpoint location and contribute to a map of haplotolerant genes
A 244 K genome-wide array based comparative genomic hybridization study was carried out in a familial translocation t(2;6)(p25;p21) balanced in the mother (SDM) and unbalanced in her daughter (SD). In the past, this translocation has allowed to localize the HLA multigene cluster to chromosome 6. Wit...
ORGANISM(S): Homo sapiens 
2008-12-31 | E-TABM-308 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of humoral resistance to the CTL after phenotypical and functional study of the resistant clone IGR-HeuR8
From a tumoral line IGR-Heu; resulting from a biopsy of the primitive tumour of a patient reached of a bronchial cancer not with small cells (NSCLC); we established; by successive co-cultures of this line with the autologous CTL (clone T H161); a resistant line to the cytotoxic lysis induced by H16...
ORGANISM(S): Homo sapiens 
2006-01-23 | E-TABM-71 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lung large cell carncinoma cells grown under hypoxic conditions and treated with STAT3 siRNA
Hypoxia-mediated inhibition of specific tumour cell lysis
ORGANISM(S): Homo sapiens 
2009-03-12 | E-TABM-611 | biostudies-arrayexpress
UnknownBiogeochemical feedbacks associated with the response of micronutrient recycling by zooplankton to climate change.
Not available
S-EPMC9292334 | biostudies-literature
UnknownExploring the Transport Path of Oceanic Microplastics in the Atmosphere.
Not available
S-EPMC11325545 | biostudies-literature
UnknownCloning and characterization of a histone deacetylase, HDAC9.
Not available
S-EPMC58507 | biostudies-literature
UnknownPreclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.
Not available
S-EPMC5654348 | biostudies-literature
TranscriptomicsIGR_DNA_DAMAGE_STUDY_FM
Granzyme B plays a key role in cell-mediated programmed cell death. We previously demonstrated that p53 is a functional determinant in the Granzyme B-induced cytotoxic T lymphocyte response. However, the pathways leading to activation of p53 by Granzyme B remain incompletely understood. We now demon...
ORGANISM(S): Homo sapiens 
2012-02-15 | E-TABM-1116 | biostudies-arrayexpress
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