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TranscriptomicsIdentification of pro-fibrotic macrophages populations by scRNA-seq in West Highland white terriers affected with canine idiopathic pulmonary fibrosis
We used the scRNA-seq to characterize disease-related heterogeneity within cell populations of macrophages/monocytes in the bronchoalveolar lavage fluid from West Highland white terriers either healthy or affected with canine idioapthic pulmonary fibrosis. The disease is still not well understood, o...
ORGANISM(S): Canis lupus familiaris 
2020-12-02 | E-MTAB-9623 | biostudies-arrayexpress
TranscriptomicsCombining transcriptomics with functional phylogenomics elucidates the ecophysiology of sulfatases in marine bacteria
We present a study combining gene expression analyses and bioinformatic assessment. 1120 sequences annotated as sulfatase encoding from eight Rhodopirellula strains were clustered into 173 groups of orthologous and paralogous genes. A selection of 709 sulfatase gene strains were aligned to 66 sulfat...
ORGANISM(S): Rhodopirellula baltica 
2012-03-31 | E-GEOD-35832 | biostudies-arrayexpress
MetabolomicsSARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular metabolism and reduces ...
2021-06-11 | MTBLS2840 | MetaboLights
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