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ProteomicsPhosphoproteome of airway epithelial cell in response to infection with Staphylococcus aureus
Here we used an unbiased proteomic and phosphoproteomic approach to characterize the response of 16HBE14o- airway epithelial cells following infection with S. aureus.
ORGANISM(S): Homo sapiens (Human) 
2016-12-14 | PXD002776 | Pride
Infection Airway epithelium Staphylococcus aureus 
MetabolomicsClenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells
Activation of the sympathetic nervous system causes pronounced metabolic changes that are mediated by multiple adrenergic receptor subtypes. Systemic treatment with β2-adrenergic receptor agonists results in multiple beneficial metabolic effects, including improved glucose homeostasis. To...
2022-08-26 | MTBLS467 | MetaboLights
TranscriptomicsChromatin based modeling of transcription rates identifies the contribution of different regulatory layers to steady-state mRNA levels.
Messenger RNA levels in eukaryotes are balanced by two consecutive regulatory layers. Primary, transcriptional regulation at the level of chromatin and secondary, post-transcriptional regulation of the initial transcript in the cytoplasm. Each layer is individually studied in mechanistic detail, whi...
ORGANISM(S): Mus musculus 
2012-09-13 | E-GEOD-34473 | biostudies-arrayexpress
GenomicsA comparative epigenomics approach reveals REST as a mediator of Polycomb reprogramming during neuronal differentiation
Transcription factors (TFs) in concert with chromatin pathways stably reset transcriptional programs during differentiation. Yet we know little how local sites of chromatin reprogramming are specified and how the estimated 3000 TF encoded in mammalian genomes contribute to chromatin dynamics. To ide...
ORGANISM(S): Mus musculus 
2012-09-04 | E-GEOD-27148 | biostudies-arrayexpress
TranscriptomicsChromatin based modeling of transcription rates identifies the contribution of different regulatory layers to steady-state mRNA levels
Messenger RNA levels in eukaryotes are balanced by two consecutive regulatory layers. Primary, transcriptional regulation at the level of chromatin and secondary, post-transcriptional regulation of the initial transcript in the cytoplasm. Each layer is individually studied in mechanistic detail, whi...
ORGANISM(S): Mus musculus 
2012-07-23 | E-GEOD-33252 | biostudies-arrayexpress
ProteomicsThe exercise-regulated skeletal muscle phosphoproteome
Four healthy male volunteers (age: 24 - 27; BMI: 24.2 - 25.9 kg/m2) underwent a single bout of high-intensity bicycle exercise reaching a VO2 max approximately 95% with blood samples and muscle biopsies taken immediately pre- and post-exercise. Subjects reached 95% VO2 max in approximately 9 to 12 m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080777 | MassIVE
UnknownPhosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry
Not available
S-SCDT-EMBOJ-2019-102578 | biostudies-other
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