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MetabolomicsComparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights
ProteomicsAntibody RING-Mediated Destruction (ARMeD) of endogenous proteins
To help understand the cellular function of a gene the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by th...
ORGANISM(S): Homo Sapiens 
2020-05-28 | PXD016193 | panorama
UnknownCompeting Michael/Anti-Michael Addition of Silyl Ketene Acetals to β-Nitrostyrenes Incorporating an Electron-Withdrawing Group.
Not available
S-EPMC12519467 | biostudies-literature
UnknownToward the Total Synthesis of Alpkinidine: Michael Addition to Isoquinolinetrione CE Ring-System Synthons.
Not available
S-EPMC9202020 | biostudies-literature
ProteomicsQuantitative XL-MS Analysis of HHARI in the presence or absence of 4EHP
RING-Between-RING (RBR) E3 ligases mediate ubiquitin transfer through an obligate E3- ubiquitin thioester intermediately prior to substrate ubiquitination. While RBRs share a conserved catalytic module, substrate recruitment mechanisms remain enigmatic and the relevant domains have yet to be identi...
ORGANISM(S): Homo Sapiens 
PXD030871 | panorama
UnknownThe Synthesis of Bio-Based Michael Donors from Tall Oil Fatty Acids for Polymer Development.
Not available
S-EPMC9572469 | biostudies-literature
UnknownBase-promoted highly efficient synthesis of nitrile-substituted cyclopropanes via Michael-initiated ring closure† † Electronic supplementary information (ESI) available: Experimental section, characterization of all compounds, copies of 1H and 13C NMR spectra for selected compounds. CCDC 2141258 and 2142244. For ESI and crystallographic data in CIF or other electronic format see DOI: https://doi.org/10.1039/d2ra05393d
Not available
S-EPMC9536251 | biostudies-literature
UnknownConformational Landscapes and Energetics of Carbon Nanohoops and their Ring-in-Ring Complexes.
Not available
S-EPMC11229059 | biostudies-literature
UnknownNew Hybrid-type Squaramide-Fused Amino Alcohol Organocatalyst for Enantioselective Domino Michael Addition/Cyclization Reaction of Oxoindolines with Cyclic 1,3-Diketones.
Not available
S-EPMC6645594 | biostudies-literature
GenomicsMouse ES cells expressing catalytically inactive Ring1B display impaired Ring1B and H3K27me3 deposition.
ChIP-seq for H3K27me3 and Ring1B was performed in WT mESCs and mESCs containing catalytically inactive Ring1B (I53A mutant). Cells expressing catalytically inactive Ring1B maintain the spatial distribution of Ring1B and H3K27me3 but at reduced levels. These findings support the notion that PRC2 recr...
ORGANISM(S): Mus musculus 
2015-09-20 | E-GEOD-69955 | biostudies-arrayexpress
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