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TranscriptomicsNF1 microdeletions characterization by custom high-resolution array CGH
To allow accute charaterization of NF1 locus constitutional microdeletion in 70 NF1 patients, a custom array CGH was developped. Goal was to obtain genomic rearrangements fine characterization in order to perform genotype-phenotype correlation in NF1 microdeleted patients. To serve as a reference g...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-19730 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of a series of 22 NF1-associated plexiform neurofibromas
22 plexiform neurofibromas from 18 unrelated neurofibromatosis-type 1 patients were screened with a high resolution array-CGH. Each PNF DNA (somatic tumor DNA) was individually hybridized on Agilent whole human genome 244K microarrays (Platform GPL4091) using the matched genomic constitutional DNA (...
ORGANISM(S): Homo sapiens 
2011-09-29 | E-GEOD-24328 | biostudies-arrayexpress
UnknownOncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers.
Not available
S-EPMC6117344 | biostudies-literature
TranscriptomicsHedgehog Molecular Networks in the Second Heart Field
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-44756 | biostudies-arrayexpress
TranscriptomicsPosterior Second Heart Field (pSHF) transcriptomes of wild-type and Shh mutant mouse embryos
To understand Sonic hedgehog homolog (Shh)-mediated molecular networks in the posterior second heart field (pSHF), we have employed whole genome microarray expression profiling as a discovery platform to identify genes with Shh-dependent expressional changes. We microdissected the pSHF from E9.5 em...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-44754 | biostudies-arrayexpress
TranscriptomicsMouse frozen liver: vehicle-control vs. CCl4+DEN treated
Hepatocellular carcinoma (HCC) is a prevalent human cancer with rising incidence worldwide. Human HCC is frequently associated with chronic liver inflammation and cirrhosis, pathophysiological processes that are a consequence of chronic viral infection, disturbances in metabolism, or exposure to che...
ORGANISM(S): Mus musculus 
2015-11-01 | E-GEOD-71849 | biostudies-arrayexpress
UnknownMetabolic signatures derived from whole-brain MR-spectroscopy identify early tumor progression in high-grade gliomas using machine learning.
Not available
S-EPMC11614968 | biostudies-literature
TranscriptomicsIdentification of circulating lncRNAs associated with gallbladder cancer risk by tissue-based preselection, cis-eQTL validation, and analysis of association with genotype-based expression
Long non-coding RNAs (lncRNAs) play key roles in cell processes and are good candidates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. Here we integrate three separate datasets with information on lncRNA expression only, ...
ORGANISM(S): Homo sapiens 
2022-01-17 | E-MTAB-11367 | biostudies-arrayexpress
UnknownWhen the wild things are: Defining mammalian diel activity and plasticity.
Not available
S-EPMC11864191 | biostudies-literature
UnknownVariation in global trauma care: a survey of 187 hospitals across 51 countries.
Not available
S-EPMC12598983 | biostudies-literature
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