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Background/Aims: Microarray-based comparative genomic hybridisation (CGH) has allowed high-resolution analysis of DNA copy number alterations across the entire cancer genome. Recent advances in bioinformatics tools enable us to perform a robust and highly sensitive analysis of array CGH data and fac...
ORGANISM(S): Homo sapiens 
Abnormalities of chromosome 7q are common in myeloid malignancies. Agilent CGH arrays targeted to 7q and Affymetrix SNP 6.0 arrays were used to characterise 7q aUPD and deletions. Sample #017 in this data series showed a microdeletion encompassing EZH2. Screening of a total of 614 cases with myeloid...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE16598: Tumor T1 Sectors GSE16599: Tumor T2 Sectors GSE16600: Tumor T3 Sectors GSE16601: Tumor T4 Sectors GSE16602: Tumor T5 Sectors GSE16603: Tumor T6 Sectors GSE16604: Tumor T7 Sectors GSE16605: Tumor T8 Sectors GSE16606: Tumor T9 Sect...
ORGANISM(S): Homo sapiens 
The following CGH experiments were conducted on four sectors (S1-S4) from a single primary ductal carcinoma tumor (T1). The genomic DNA from each tumor sector was labeled with Cy5 and hybridized to an 85K Bgl2 ROMA Microarray. A normal reference male fibroblast was labeled with Cy3 as a control. S...
ORGANISM(S): Homo sapiens 
The following CGH experiments were conducted on four sectors (S1-S4) from a single primary ductal carcinoma tumor (T4). The genomic DNA from each tumor sector was labeled with Cy5 and hybridized to an 85K Bgl2 ROMA Microarray. A normal reference male fibroblast was labeled with Cy3 as a control. ...
ORGANISM(S): Homo sapiens 
The following CGH experiments were conducted on four sectors (S1-S4) from a single primary ductal carcinoma tumor (T3). The genomic DNA from each tumor sector was labeled with Cy5 and hybridized to an 85K Bgl2 ROMA Microarray. A normal reference male fibroblast was labeled with Cy3 as a control. ...
ORGANISM(S): Homo sapiens 
The following CGH experiments were conducted on four sectors (S1-S4) from a single primary ductal carcinoma tumor (T2). The genomic DNA from each tumor sector was labeled with Cy5 and hybridized to an 85K Bgl2 ROMA Microarray. A normal reference male fibroblast was labeled with Cy3 as a control. S...
ORGANISM(S): Homo sapiens 
The following CGH experiments were conducted on six sectors (S1-S6) from a single primary ductal carcinoma tumor (T9) using the Sector-Ploidy-Profiling (SPP) Approach. SPP involves macro-dissecting the tumor, flow-sorting nuclei by differences in total genomic DNA content and profiling the genome o...
ORGANISM(S): Homo sapiens 
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