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TranscriptomicsSingle cell RNA-sequencing of PBMC derived B cells from human healthy donor
Motivation: The B-cell receptor (BCR) performs essential functions for the adaptive immune system including recognition of pathogen-derived antigens. The vast repertoire and adaptive variation of BCR sequences due to V(D)J recombination and somatic hypermutation (SHM) necessitates single-cell charac...
ORGANISM(S): Homo sapiens 
2018-06-22 | E-MTAB-6386 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of antigen-specific T cells at the single-cell level after clearance of hepatitis C virus
We used scRNA-seq data generated using Smart-seq2 to reconstruct the native TCR from Ag-specific T cells and then to link these with the gene expression profile of individual cells. antigen specific CD8 T cells were obtained from a subject who had previously cleared hepatitis C virus (HCV) infection...
ORGANISM(S): Homo sapiens 
2017-01-31 | E-MTAB-4850 | biostudies-arrayexpress
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