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UnknownsnR30/U17 Small Nucleolar Ribonucleoprotein: A Critical Player during Ribosome Biogenesis.
Not available
S-EPMC7601244 | biostudies-literature
UnknownZika virus remodels and hijacks IGF2BP2 ribonucleoprotein complex to promote viral replication organelle biogenesis.
Not available
S-EPMC11578589 | biostudies-literature
TranscriptomicsRNA clamping by Vasa assembles a piRNA Amplifier complex on transposon transcripts
Germline-specific Piwi-interacting RNAs (piRNAs) protect the genome against selfish genetic elements and are essential for fertility in animals. piRNAs targeting active transposons are amplified by a feed-forward loop known as the Ping-pong cycle, which links endonucleolytic slicing of target RNA...
ORGANISM(S): Bombyx mori 
2014-06-04 | E-GEOD-57420 | biostudies-arrayexpress
ProteomicsA compendium of RNA-binding proteins that regulate microRNA biogenesis
During microRNA-biogenesis, stem-loop structured precursors are processed in two endonucleolytic steps, giving rise to mature microRNAs (miRNAs). This process is not only regulated at the level of transcription but also posttranscriptionally by RNA-binding proteins (RBPs). Here we have used a proteo...
ORGANISM(S): Homo sapiens (Human) 
2017-04-26 | PXD004193 | Pride
Mass spectrometry Microrna Rna-protein interaction 
TranscriptomicsIn depth analysis of the interaction of HIV 1 with cellular microRNA biogenesis and effector mechanisms
The question of how HIV 1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4+ PBMCs and...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-59944 | biostudies-arrayexpress
TranscriptomicsTranscriptome maps of mRNP biogenesis factors define pre-mRNA recognition
Biogenesis of eukaryotic messenger ribonucleoprotein complexes (mRNPs) involves the synthesis, splicing, and 3M-bM-^@M-^Y-processing of pre-mRNA, and the assembly of mature mRNPs for nuclear export. We mapped 23 mRNP biogenesis factors onto the newly synthesized yeast transcriptome, providing ~10^5-...
ORGANISM(S): Saccharomyces cerevisiae 
2014-07-23 | E-GEOD-59676 | biostudies-arrayexpress
TranscriptomicsPerturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome (RNA-seq dataset)
In order to dissect the nuclear RNA quality control (QC) mechanisms, we used a powerful assay based on global perturbation of mRNP biogenesis in yeast Saccharomyces cerevisiae by the bacterial Rho helicase. We have monitored the global RNA levels upon Rho activation and compare it to basal RNA level...
ORGANISM(S): Saccharomyces cerevisiae 
2019-12-04 | E-MTAB-7538 | biostudies-arrayexpress
UnknownHNRNPD regulates the biogenesis of circRNAs and the ratio of mRNAs to circRNAs for a set of genes.
Not available
S-EPMC11346550 | biostudies-literature
GenomicsPerturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome (ChIP-seq dataset)
In order to dissect the nuclear RNA quality control (QC) mechanisms, we used a powerful assay based on global perturbation of mRNP biogenesis in yeast Saccharomyces cerevisiae by the bacterial Rho helicase. We have monitored the global RNA levels upon Rho activation and compare it to basal RNA level...
ORGANISM(S): Saccharomyces cerevisiae 
2019-12-04 | E-MTAB-7539 | biostudies-arrayexpress
UnknownBiogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits.
Not available
S-EPMC6797745 | biostudies-literature
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