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ProteomicsShort duplex RNAs induce potent immunostimulation via Hoogsteen G-G base pairing-mediated dimerization
Here we describe a new class of immunostimulatory short duplex RNAs that potently induce production of type I interferon (IFN-I), and particularly IFN-β, in a wide range ofhuman cell types via end-to-end dimerization, direct binding to RIG-I, and activation of the RIG-I/IRF3 pathway. These RNAs requ...
ORGANISM(S): Homo sapiens (Human) 
2022-09-01 | PXD027838 | Pride
Type i interferon Lung chips Sars-cov-2 Immune stimulation Short duplex rna 
ProteomicsINO80E_HIRIP3_RNA_duplex_proteins_RAP_MS
MS data from the RAP-MS experiment performed for identyfication of proteins that interact with HIRIP3 and INO80E RNA duplex.
ORGANISM(S): Homo sapiens (Human) 
2025-02-21 | PXD060587 | Pride
Rna duplex  ino80e  hirip3 
UnknownRNA⁻Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.
Not available
S-EPMC6321275 | biostudies-literature
UnknownBase pairing and structural insights into the 5-formylcytosine in RNA duplex.
Not available
S-EPMC4889945 | biostudies-literature
UnknownInfluence of C-5 halogenation of uridines on hairpin versus duplex RNA folding.
Not available
S-EPMC1950758 | biostudies-literature
UnknownA newly identified duplex RNA unwinding activity of archaeal RNase J depends on processive exoribonucleolysis coupled steric occlusion by its structural archaeal loops.
Not available
S-EPMC7549665 | biostudies-literature
UnknownStructure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Not available
S-EPMC9279153 | biostudies-literature
UnknownSynthesis of native-like crosslinked duplex RNA and study of its properties.
Not available
S-EPMC5969911 | biostudies-literature
TranscriptomicsSorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
In flies, small silencing RNAs are sorted between Argonaute1 (Ago1), the central protein component of the microRNA (miRNA) pathway, and Argonaute2 (Ago2), which mediates RNA interference. Extensive double-stranded characterM-bM-^@M-^Tas is found in small interfering RNAs (siRNAs)M-bM-^@M-^Tdirects d...
ORGANISM(S): Drosophila melanogaster 
2009-10-31 | E-GEOD-18806 | biostudies-arrayexpress
UnknownRecognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2.
Not available
S-EPMC4333395 | biostudies-literature
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