Using RNAseq we describe transcriptional changes downstream of liver-specific knockout of RNaseH1, including effects on mitochondrial function, fibrosis and cell cycle
Endonuclease RNaseH1 acts as a common R-loop resolvase to prevent R-loop accumulation genome-widely, whether there is any exonuclease complementing RNaseH1 to more efficiently resolve R-loops is worth investigation. Here we identify an exonuclease REXO4, which collaborates with RNaseH1 to efficientl...
