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ProteomicsRNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer
Wnt/b-catenin signaling is a primary pathway for stem cell maintenance during tissue renewal and a frequent target for mutations in cancer. Impaired Wnt receptor endocytosis due to loss of the ubiquitin ligase RNF43 gives rise to Wnt-hypersensitive tumors that are susceptible to anti-Wnt-based thera...
ORGANISM(S): Homo sapiens (Human) 
2020-08-14 | PXD020478 | Pride
Porcn inhibitors Cancer mutations Rnf 43 Human colon organoids Wnt signaling Lc-ms/ms 
ModelsScott2024 - Genome-scale metabolic model of Clostridium luticellarii
No description
2025-03-15 | MODEL2411260001 | BioModels
ModelsMostolizadeh2022 - D. pigrum and S. aureus
This resulting community model combines the latest available curated GEMs of D. pigrum and S. aureus. This use-case illustrates how to incorporate genuine GEMs of participating microorganisms and creates a basic community model mimicking the human nasal environment.
2022-10-15 | MODEL2209060002 | BioModels
UnknownScott2024 - Genome-scale metabolic model of Clostridium luticellarii
Not available
MODEL2411260001 | biostudies-other
UnknownMostolizadeh2022 - D. pigrum and S. aureus
Not available
MODEL2209060002 | biostudies-other
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