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To evaluate gene expression in human peripheral blood derived monocytes over the course of an LPS stimulation time-series. Experiment Overall Design: Blood samples from three individuals, each sample split into separate culture for each timepoint (0, 2, 4, 8, and 24 hours). RNA prepared from all, an...
ORGANISM(S): Homo sapiens 

The overall goal of this project is to investigate the etiology and pathogenesis of malformations (i.e., birth defects) of the limb, concentrating on abnormalities of limb patterning such as limb deficiency/duplications and multiple congenital contractures.

The exome sequences of two s...

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