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MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
TranscriptomicsU2AF1 mutations alter splice site recognition in hematological malignancies
Whole-exome sequencing studies have identified common mutations affecting genes encoding components of the RNA splicing machinery in hematological malignancies. Here, we sought to determine how mutations affecting the 3' splice site recognition factor U2AF1 altered its normal role in RNA splicing. W...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58871 | biostudies-arrayexpress
UnknownImpact of social service and public health spending on teenage birth rates across the USA: an ecological study.
Not available
S-EPMC5541339 | biostudies-literature
TranscriptomicsTranscription profiling of E.coli Fis knockout strain
Fis is a nucleoid-associated protein in E. coli that is abundant during early logarithmic growth in rich medium but is in short supply during stationary phase. Its role as a transcriptional regulator has been demonstrated for an increasing number of genes. In order to gain insight into the global ...
ORGANISM(S): Escherichia coli 
2008-06-15 | E-GEOD-7379 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E.coli wild type (Fis+) strain
Fis is a nucleoid-associated protein in E. coli that is abundant during early logarithmic growth in rich medium but is in short supply during stationary phase. Its role as a transcriptional regulator has been demonstrated for an increasing number of genes. In order to gain insight into the global ...
ORGANISM(S): Escherichia coli 
2008-06-15 | E-GEOD-7380 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli covering four phases of growth in Fis KO and WT (Fis+) strains
This SuperSeries is composed of the following subset Series:; GSE7379: Fis KO strain; GSE7380: WT (Fis+) strain Experiment Overall Design: Refer to individual Series
ORGANISM(S): Escherichia coli 
2008-06-15 | E-GEOD-7398 | biostudies-arrayexpress
UnknownImpact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.
Not available
S-EPMC5455690 | biostudies-literature
UnknownOptimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer.
Not available
S-EPMC5455310 | biostudies-literature
UnknownGPT2 mutations in autosomal recessive developmental disability: extending the clinical phenotype and population prevalence estimates.
Not available
S-EPMC6748651 | biostudies-literature
TranscriptomicsTranscription profiling of mice hearts comparing microRNA-22 overexpression to wildtype
To explore the role of miR-22 in the heart, we generated miR-22 null and transgenic mice. Cardiac transgenic overexpression of miR-22 in vivo led to cardiac hypertrophy that evolved into progressive dilated cardiomyopathy (DCM) in unstressed hearts. We found that miR-22 directly regulates two transc...
ORGANISM(S): Mus musculus 
2012-12-01 | E-MTAB-501 | biostudies-arrayexpress
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