Sort   by:  
 Page size 
TranscriptomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: RNAseq
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modeled this leukemic evolution through s...
ORGANISM(S): Homo sapiens 
2022-09-29 | E-MTAB-11033 | biostudies-arrayexpress
UnknownInformed consent for neonatal trials: practical points to consider and a check list.
Not available
S-EPMC7778778 | biostudies-literature
UnknownDendritic Cells or Macrophages? The Microenvironment of Human Clear Cell Renal Cell Carcinoma Imprints a Mosaic Myeloid Subtype Associated with Patient Survival.
Not available
S-EPMC9600747 | biostudies-literature
TranscriptomicsPrimary human CD34+ cells for modeling ETO2-GLIS2 leukemogenesis - Bulk RNAseq
Several fusion oncogenes showing a higher incidence in pediatric acute myeloid leukemia are associated with heterogeneous megakaryoblastic and other myeloid features. Here we addressed how developmental mechanisms influence human leukemogenesis by ETO2::GLIS2, a hallmark of dismal prognosis. We ind...
ORGANISM(S): Homo sapiens 
2024-10-08 | E-MTAB-14131 | biostudies-arrayexpress
TranscriptomicsPrimary human CD34+ cells for modeling ETO2-GLIS2 leukemogenesis - ATACseq
To understand the early consequences of cytokine stimulation, we performed chromatin accessibility assay (ATAC-seq) on primary human CD34+ fetal and cord blood cells exposed or not to IL3 and SCF for 5 days in vitro.
ORGANISM(S): Homo sapiens 
2024-10-08 | E-MTAB-14124 | biostudies-arrayexpress
TranscriptomicsPrimary human CD34+ cells for modeling ETO2-GLIS2 leukemogenesis - Single cell RNAseq
To characterize the consequences of cytokine stimulation, we compared ET02-GLIS2 expressing cells from different origins by single cell transcriptomes (scRNAseq). We analysed FL and CB ET02-GLIS2-expressing CD34+ progeny after 7 days in vitro, human cells from diseased NSG (FL- and FBM-derived) and ...
ORGANISM(S): Homo sapiens 
2024-10-08 | E-MTAB-14140 | biostudies-arrayexpress
UnknownPaediatric clinical research in Europe: an insight on experts' needs and perspectives.
Not available
S-EPMC7905444 | biostudies-literature
UnknownPharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open-label clinical trial.
Not available
S-EPMC6089805 | biostudies-literature
UnknownTransethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome.
Not available
S-EPMC6050942 | biostudies-literature
UnknownIncidence, prevalence and clinical presentation of inflammatory bowel diseases in Northern France: a 30-year population-based study.
Not available
S-EPMC11522416 | biostudies-literature
Sort   by:  
 Page size