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ProteomicsProteomic characterization of ESR1 mutant cells
Three quarters of all breast cancer cases express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancers, in particular to aromatase inhibitors....
ORGANISM(S): Homo sapiens (Human) 
2024-03-26 | PXD032369 | Pride
Esr1 mutation Breast cancer 
ProteomicsPhosphoproteome characterization of ESR1 mutated breast cancer cells
Three quarters of all breast cancer cases express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancers, in particular to aromatase inhibitors....
ORGANISM(S): Homo sapiens (Human) 
2024-03-26 | PXD032285 | Pride
Phosphoproteome Esr1 mutations Breast cancer 
TranscriptomicsRNA Sequencing Quantitative Analysis of cell lines derived from tumours from two mouse models of human osteosarcoma that recapitulate clinically distinct human osteosarcoma subtypes.
Purpose: Osteosarcoma (OS) is the most common primary bone malignancy. OS consists of several subtypes including fibroblastic, osteoblastic and chondroblastic OS. We have developed genetically engineered mouse models of human OS that recapitulate two distinct subtypes, fibroblastic (Osx-CreLox p53-/...
ORGANISM(S): Mus musculus 
2015-07-06 | E-GEOD-58916 | biostudies-arrayexpress
TranscriptomicsWnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma
Purpose: We have used microarrays to identify gene expression profiles that distinguish mouse OS cells from normal pre-osteoblast cells and mature osteoblast cells. Methods: Transcriptional profiles of three cell lines derived from tumors from Osx-Cre p53fl/fl Rbfl/fl (fibroblastic OS) mouse model, ...
ORGANISM(S): Mus musculus 
2015-01-29 | E-GEOD-63939 | biostudies-arrayexpress
UnknownCyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma.
Not available
S-EPMC4645454 | biostudies-literature
UnknownFirst symptoms and health care pathways in hospitalized patients with acute heart failure: ICPS2 survey. A report from the Heart Failure Working Group (GICC) of the French Society of Cardiology.
Not available
S-EPMC8364729 | biostudies-literature
UnknownEstimating overdiagnosis in giant cell arteritis diagnostic pathways using genetic data: genetic association study.
Not available
S-EPMC11292050 | biostudies-literature
ProteomicsLC7 Proteomic Analysis of Matched Control and NSCLC Lung Adenocarcinoma Tissue.
Non-small cell lung adenocarcinoma is the most frequently diagnosed lung cancer type and remains the leading cause of cancer mortality for men and women in the United States. Management of lung cancer is hindered by high false-positive rates due to the inability to resolve benign versus malignant tu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080825 | MassIVE
UnknownA genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.
Not available
S-EPMC10439125 | biostudies-literature
UnknownComprehensive genotype-phenotype analysis in POLR3-related disorders.
Not available
S-EPMC12391809 | biostudies-literature
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