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GenomicsBromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (ChIP-Seq)
Pharmacological inhibition of chromatin co-regulatory factors represents a clinically validated strategy to modulate oncogenic signaling through selective attenuation of gene expression. Here, we demonstrate that CBP/EP300 bromodomain inhibition preferentially abrogates the viability of multiple mye...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-71909 | biostudies-arrayexpress
UnknownAssociations between endogenous sex hormones and FGF-23 among women and men in the Multi-Ethnic Study of Atherosclerosis.
Not available
S-EPMC9132299 | biostudies-literature
TranscriptomicsGenome-wide measurement of RNA folding energies
RNA structural transitions are important in the function and regulation of RNAs. Here, we reveal a layer of transcriptome organization in the form of RNA folding energies. By probing yeast RNA structures at different temperatures, we obtained relative melting temperatures (Tm) for RNA structures in ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-09 | E-GEOD-39680 | biostudies-arrayexpress
UnknownPhase II Clinical Trial and Preclinical Evaluation of a Novel CD47 Blockade Combination in Refractory Microsatellite-Stable Metastatic Colorectal Cancer.
Not available
S-EPMC12631056 | biostudies-literature
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
UnknownRecommendations on RBC Transfusion in General Critically Ill Children Based on Hemoglobin and/or Physiologic Thresholds From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.
Not available
S-EPMC6125789 | biostudies-literature
UnknownCardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study.
Not available
S-EPMC11406334 | biostudies-literature
UnknownDeterminants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Not available
S-EPMC7480059 | biostudies-literature
UnknownPatterns of Organ Dysfunction in Critically Ill Children Based on PODIUM Criteria.
Not available
S-EPMC9271339 | biostudies-literature
UnknownPrevalence and Risk Factors for Kidney Disease and Elevated BP in 2-Year-Old Children Born Extremely Premature.
Not available
S-EPMC9435989 | biostudies-literature
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